Babacan Nalan Akgul, Kiliçkap Saadettin, Sene Soner, Kacan Turgut, Yucel Birsen, Eren Mehmet Fuat, Cihan Sener
Department of Medical Oncology, Cumhuriyet University, Sivas, Turkey.
Department of Medical Oncology, Hacettepe University Ankara, Turkey.
Indian J Dermatol. 2015 Mar-Apr;60(2):213. doi: 10.4103/0019-5154.152582.
Although cutaneous metastasis occurs usually at the terminal stage of the disease, it may be rarely concurrent with the diagnosis and may also present as the first sign of the illness. A 55-year-old male patient presented with vasculitic-type cutaneous nodular lesions and a necrotic distal phalangeal lesion developed over the last month. He was a tradesman and smoked 40 packets year. On physical examination, he was found to have multiple cutaneous lesions on the skin of the face, limbs, neck, scalp, dorsal side, fingers, subungual side, right leg, and feet. A skin lesion punch biopsy was performed and squamous cell carcinoma metastasis was detected. He was diagnosed as having squamous cell lung cancer with bronchoscopic biopsy. Although it is very rare, cutaneous metastases that is concurrent with the diagnosis of lung cancer may be the first sign of the disease. In patients with suspicious skin lesions, the patient's age, smoking history, and other symptoms should be evaluated and a biopsy should be performed.
虽然皮肤转移通常发生在疾病的晚期，但它可能很少与诊断同时出现，也可能表现为疾病的首发症状。一名55岁男性患者出现血管炎型皮肤结节性病变，且在过去一个月内远端指骨出现坏死性病变。他是一名商人，每年吸烟40包。体格检查发现，他的面部、四肢、颈部、头皮、背部、手指、甲下侧、右腿和足部皮肤有多处皮肤病变。进行了皮肤病变穿刺活检，检测到鳞状细胞癌转移。经支气管镜活检，他被诊断为鳞状细胞肺癌。虽然非常罕见，但与肺癌诊断同时出现的皮肤转移可能是该疾病的首发症状。对于有可疑皮肤病变的患者，应评估患者的年龄、吸烟史和其他症状，并进行活检。
