急性呼吸窘迫综合征
The acute respiratory distress syndrome.
作者信息
Modrykamien Ariel M, Gupta Pooja
机构信息
Division of Pulmonary and Critical Care Medicine, Baylor University Medical Center at Dallas, Dallas, Texas (Modrykamien), and the Division of Pulmonary, Sleep, and Critical Care Medicine, Creighton University Medical Center, Omaha, Nebraska (Gupta).
出版信息
Proc (Bayl Univ Med Cent). 2015 Apr;28(2):163-71. doi: 10.1080/08998280.2015.11929219.
Abstract
The acute respiratory distress syndrome (ARDS) is a major cause of acute respiratory failure. Its development leads to high rates of mortality, as well as short- and long-term complications, such as physical and cognitive impairment. Therefore, early recognition of this syndrome and application of demonstrated therapeutic interventions are essential to change the natural course of this devastating entity. In this review article, we describe updated concepts in ARDS. Specifically, we discuss the new definition of ARDS, its risk factors and pathophysiology, and current evidence regarding ventilation management, adjunctive therapies, and intervention required in refractory hypoxemia.
摘要
急性呼吸窘迫综合征（ARDS）是急性呼吸衰竭的主要原因。其发展会导致高死亡率以及短期和长期并发症，如身体和认知功能障碍。因此，早期识别该综合征并应用已证实的治疗干预措施对于改变这种毁灭性疾病的自然病程至关重要。在这篇综述文章中，我们描述了ARDS的最新概念。具体而言，我们讨论了ARDS的新定义、其危险因素和病理生理学，以及关于通气管理、辅助治疗和难治性低氧血症所需干预措施的当前证据。
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本文引用的文献
1
Prone positioning in severe acute respiratory distress syndrome.俯卧位通气治疗严重急性呼吸窘迫综合征。
N Engl J Med. 2013 Jun 6;368(23):2159-68. doi: 10.1056/NEJMoa1214103. Epub 2013 May 20.
2
High-frequency oscillation in early acute respiratory distress syndrome.早期急性呼吸窘迫综合征中的高频振荡。
N Engl J Med. 2013 Feb 28;368(9):795-805. doi: 10.1056/NEJMoa1215554. Epub 2013 Jan 22.
3
High-frequency oscillation for acute respiratory distress syndrome.高频振荡治疗急性呼吸窘迫综合征。
N Engl J Med. 2013 Feb 28;368(9):806-13. doi: 10.1056/NEJMoa1215716. Epub 2013 Jan 22.
4
Tidal volume, recruitment and compliance in HFOV: same principles, different frequency.高频振荡通气中的潮气量、肺复张和顺应性：原理相同，频率不同。
Eur Respir J. 2012 Aug;40(2):291-3. doi: 10.1183/09031936.00020012.
5
Acute respiratory distress syndrome: the Berlin Definition.急性呼吸窘迫综合征：柏林定义。
JAMA. 2012 Jun 20;307(23):2526-33. doi: 10.1001/jama.2012.5669.
6
The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks.意大利体外膜肺氧合网络在 2009 年甲型 H1N1 流感大流行期间的经验：为严重呼吸道紧急疫情爆发做准备。
Intensive Care Med. 2011 Sep;37(9):1447-57. doi: 10.1007/s00134-011-2301-6. Epub 2011 Jul 6.
7
Active and passive cigarette smoking and acute lung injury after severe blunt trauma.主动和被动吸烟与严重钝性创伤后急性肺损伤。
Am J Respir Crit Care Med. 2011 Jun 15;183(12):1660-5. doi: 10.1164/rccm.201011-1802OC. Epub 2011 Mar 18.
8
Airway pressure release ventilation: an alternative mode of mechanical ventilation in acute respiratory distress syndrome.气道压力释放通气：急性呼吸窘迫综合征的一种机械通气方式。
Cleve Clin J Med. 2011 Feb;78(2):101-10. doi: 10.3949/ccjm.78a.10032.
9
Influence of body mass index on outcome of the mechanically ventilated patients.体重指数对机械通气患者预后的影响。
Thorax. 2011 Jan;66(1):66-73. doi: 10.1136/thx.2010.145086. Epub 2010 Oct 27.
10
Neuromuscular blockers in early acute respiratory distress syndrome.早期急性呼吸窘迫综合征中的神经肌肉阻滞剂。
N Engl J Med. 2010 Sep 16;363(12):1107-16. doi: 10.1056/NEJMoa1005372.
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