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Evaluation of pH, calcium ion release and antimicrobial activity of a new calcium aluminate cement.新型铝酸钙水泥的 pH 值、钙离子释放和抗菌活性评价。
Braz Oral Res. 2013 Jul-Aug;27(4):324-30. doi: 10.1590/s1806-83242013000400006.
2
Mineral trioxide aggregate with anti-washout gel - properties and microstructure.矿化三氧化物凝聚体加抗水胶体——性能与微观结构。
Dent Mater. 2013 Mar;29(3):294-306. doi: 10.1016/j.dental.2012.11.009. Epub 2012 Dec 17.
3
Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite.银沸石掺入矿物三氧化物聚合体的短期抗菌性能。
Dent Traumatol. 2011 Jun;27(3):189-94. doi: 10.1111/j.1600-9657.2011.00986.x. Epub 2011 Apr 4.
4
Evaluation of mineral trioxide aggregate and calcium hydroxide cement as pulp-capping agents in human teeth.评估三氧化矿物凝聚体和氢氧化钙水门汀作为人类牙齿盖髓剂的效果。
J Endod. 2008 Jan;34(1):1-6. doi: 10.1016/j.joen.2007.09.012.
5
Evaluation of the antifungal effects of mineral trioxide aggregate materials.三氧化矿物凝聚体材料抗真菌效果的评估
Aust Endod J. 2006 Dec;32(3):120-2. doi: 10.1111/j.1747-4477.2006.00032.x.
6
On the causes of persistent apical periodontitis: a review.关于慢性根尖周炎病因的综述
Int Endod J. 2006 Apr;39(4):249-81. doi: 10.1111/j.1365-2591.2006.01099.x.
7
Properties of a new root-end filling material.一种新型根尖充填材料的性能
J Endod. 2005 Sep;31(9):665-8. doi: 10.1097/01.don.0000157993.89164.be.
8
In vitro antimicrobial activity of Fill Canal, Sealapex, Mineral Trioxide Aggregate, Portland cement and EndoRez.根管充填剂、Sealapex、三氧化矿物凝聚体、波特兰水泥和EndoRez的体外抗菌活性
Int Endod J. 2005 Aug;38(8):539-43. doi: 10.1111/j.1365-2591.2005.00984.x.
9
Evaluation of antifungal activity of mineral trioxide aggregate.三氧化矿物凝聚体抗真菌活性的评估。
J Endod. 2003 Dec;29(12):826-7. doi: 10.1097/00004770-200312000-00010.
10
Identification of hard tissue after experimental pulp capping using dentin sialoprotein (DSP) as a marker.以牙本质涎蛋白（DSP）为标志物，对实验性牙髓盖髓术后的硬组织进行鉴定。
J Endod. 2003 Oct;29(10):646-50. doi: 10.1097/00004770-200310000-00008.

使用试管稀释法评估两种新材料的最低抑菌浓度：一项体外研究。

Evaluation of minimal inhibitory concentration of two new materials using tube dilution method: An in vitro study.

作者信息

Hiremath Geeta S, Kulkarni Raghavendra D, Naik Balaram D

机构信息

Department of Conservative Dentistry and Endodontics, Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Dharwad, Karnataka, India.

Department of Microbiology, Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Dharwad, Karnataka, India.

出版信息

J Conserv Dent. 2015 Mar-Apr;18(2):159-62. doi: 10.4103/0972-0707.153056.

DOI:10.4103/0972-0707.153056
PMID:25829698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4379659/
Abstract

AIM

The aim of the study is to evaluate and compare the antimicrobial efficacy of two new materials MTA Plus and Biodentine with ProRoot MTA using tube dilution method.

MATERIALS AND METHODS

The materials used were ProRoot MTA (Dentsply), MTA Plus (compounded by Prevest Denpro, Jammu, India for Avalon Biomed Inc, USA) and a calcium silicate based material Biodentine (Septodont, Saint-Maur-des-Fosses, France). Doubling dilutions of the material were prepared in Sabouraud's dextrose broth (SDB) and Brain Heart Infusion (BHI) broth for Candida albicans and Enterococcus faecalis, respectively. The minimal concentration at which inhibition of microorganism occurred was measured and noted as minimal inhibitory concentration (MIC) of the material.

RESULTS

There was no statistically significant difference between the materials against C. albicans. Biodentine was statistically significant than MTA Plus against E. faecalis (P-value-0.022). ProRoot MTA was statistically significant at different time intervals against E. faecalis (P-value-0.001).

CONCLUSION

ProRoot MTA and Biodentine proved to have antimicrobial property. MTA Plusproved as a good antifungal agent.

摘要

目的

本研究旨在采用试管稀释法评估并比较两种新材料MTA Plus和Biodentine与ProRoot MTA的抗菌效果。

材料与方法

所用材料为ProRoot MTA（登士柏公司）、MTA Plus（由印度查谟的Prevest Denpro公司为美国阿瓦隆生物医学公司配制）和一种硅酸钙基材料Biodentine（法国圣莫尔-德福塞的Septodont公司）。分别在沙氏葡萄糖肉汤（SDB）和脑心浸液（BHI）肉汤中对材料进行双倍稀释，用于白色念珠菌和粪肠球菌的培养。测量并记录抑制微生物生长的最低浓度，作为该材料的最低抑菌浓度（MIC）。

结果

各材料对白色念珠菌的抗菌效果无统计学显著差异。Biodentine对粪肠球菌的抗菌效果在统计学上显著优于MTA Plus（P值 = 0.022）。ProRoot MTA在不同时间间隔对粪肠球菌的抗菌效果具有统计学显著性（P值 = 0.001）。

结论

ProRoot MTA和Biodentine具有抗菌性能。MTA Plus被证明是一种良好的抗真菌剂。