Mamabolo Ramoteme L, Sparks Martinique, Moss Sarah J, Monyeki Makama A
Department of Nutrition, School of Health Sciences, University of Venda, Thohoyandou, South Africa ; Centre of Excellence for Nutrition, Faculty of Health Sciences, North-West University (Potchefstroom Campus), Potchefstroom, South Africa.
School of Biokinetics, Recreation and Sport Science, Faculty of Health Sciences, North-West University (Potchefstroom Campus), Potchefstroom, South Africa.
Afr Health Sci. 2014 Dec;14(4):929-38. doi: 10.4314/ahs.v14i4.23.
The dyslipidemia associated with excess weight is a risk for cardiovascular disease. Worldwide and in South Africa adolescent obesity has been reported.
To determine the association between dyslipidemia and anthropometric indices in black and white adolescents.
The study involved 129 black and 69 white adolescents aged 12 to 16 years. Data collected included height, weight, waist circumference (WC) and skinfolds, blood pressure and blood for glucose, insulin, total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), triglycerides (Trig) and C - reactive protein (CRP).
WC correlated negatively with HDL in both blacks (p=0.042) and whites (p=0.008) and in whites it correlated positively with LDL (p=0.006); TC/HDL (p=<0.001) and LDL/HDL ratio (p<0.0001). WC/Hgt correlated negatively with HDL (p=0.028) and positively with LDL/HDL (p=0.026 and p<0.0001) in both races. In whites positive correlations were between WC/Hgt and TC (p=0.049); LDL (p=0.003) and TC/HDL (p<0.0001). BAZ correlated positively with TC/HDL ratio (p=0.004) and LDL/HDL ratio (p=0.002). The most common abnormalities were HDL and LDL.
Whites exhibited more associations between dyslipidemia and anthropometric indicators as compared to Blacks, suggesting that there might be differences in the lipid metabolism or even susceptibility to risk factors in adolescents.
与超重相关的血脂异常是心血管疾病的一个风险因素。全球范围内以及在南非，青少年肥胖问题均有报道。
确定黑人和白人青少年血脂异常与人体测量指标之间的关联。
该研究纳入了129名12至16岁的黑人青少年和69名白人青少年。收集的数据包括身高、体重、腰围（WC）和皮褶厚度、血压以及血糖、胰岛素、总胆固醇（TC）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、甘油三酯（Trig）和C反应蛋白（CRP）的血液样本。
在黑人（p = 0.042）和白人（p = 0.008）中，腰围均与高密度脂蛋白呈负相关，在白人中，腰围与低密度脂蛋白呈正相关（p = 0.006）；与总胆固醇/高密度脂蛋白（p < 0.001）和低密度脂蛋白/高密度脂蛋白比值呈正相关（p < 0.0001）。在两个种族中，腰围/身高与高密度脂蛋白呈负相关（p = 0.028），与低密度脂蛋白/高密度脂蛋白呈正相关（p = 0.026和p < 0.0001）。在白人中，腰围/身高与总胆固醇（p = 0.049）、低密度脂蛋白（p = 0.003）和总胆固醇/高密度脂蛋白呈正相关（p < 0.0001）。体脂面积指数与总胆固醇/高密度脂蛋白比值呈正相关（p = 0.004），与低密度脂蛋白/高密度脂蛋白比值呈正相关（p = 0.002）。最常见的异常是高密度脂蛋白和低密度脂蛋白。
与黑人相比，白人血脂异常与人体测量指标之间的关联更多，这表明青少年在脂质代谢甚至对风险因素的易感性方面可能存在差异。
