Vieira Cunha Lima S C, Oliveira Lyra C, Galvão Bacurau Pinheiro L, Medeiros de Azevedo P R, Arrais R F, Campos Pedrosa L F
Health Sciences Post Graduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Nutr Hosp. 2011 Mar-Apr;26(2):304-10. doi: 10.1590/S0212-16112011000200010.
The dyslipidemia associated with excess weight is a risk profile global call for cardiovascular disease (CVD). The aim of this study was to investigate the association between dyslipidemias and other risk factors for cardiovascular diseases (CVD) in adolescents, considering sexual maturation. A cross-sectional study was carried out with 432 adolescents from public schools, aged 10-19 years. The correlations between the variables from the lipid profile and the Body Mass Index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), sexual maturation, familial history and maternal education were evaluated using Pearson's correlation coefficient. Low high-density lipoprotein cholesterol (HDL-C) was the most prevalent dyslipidemia (50.5%), regardless of gender. There were significant correlations between triglycerides and BMI (r = 0.30, p<0.01), WC (r = 0.32, p < 0.01) and WHtR (r = 0.33, p < 0.01). The linear model, which took into consideration sexual maturation, age and BMI, explain about 1 to 10.4% of the lipid profile variation. The low HDL-c was the most prevalent dyslipidemia in all adolescents and hypertriglyceridemia was most prevalent in overweight adolescents. Associations between dyslipidemias and anthropometric indicators (BMI and RCA) detected in this study can generate the hypothesis of the risk factors for CVD in adolescents.
与超重相关的血脂异常是心血管疾病（CVD）的一个全球性风险特征。本研究的目的是探讨青少年血脂异常与心血管疾病（CVD）其他危险因素之间的关联，并考虑性成熟情况。对432名来自公立学校、年龄在10至19岁的青少年进行了一项横断面研究。使用Pearson相关系数评估了血脂谱变量与体重指数（BMI）、腰围（WC）、腰高比（WHtR）、性成熟、家族病史和母亲教育程度之间的相关性。无论性别，低高密度脂蛋白胆固醇（HDL-C）是最常见的血脂异常（50.5%）。甘油三酯与BMI（r = 0.30，p<0.01）、WC（r = 0.32，p < 0.01）和WHtR（r = 0.33，p < 0.01）之间存在显著相关性。考虑到性成熟、年龄和BMI的线性模型解释了约1%至10.4%的血脂谱变化。低HDL-c是所有青少年中最常见的血脂异常，高甘油三酯血症在超重青少年中最常见。本研究中检测到的血脂异常与人体测量指标（BMI和RCA）之间的关联可以产生青少年CVD危险因素的假设。
