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慢性前列腺炎评估中微生物学检查结果的诊断考量与解读

Diagnostic considerations and interpretation of microbiological findings for evaluation of chronic prostatitis.

作者信息

Krieger J N, McGonagle L A

机构信息

Department of Urology, University of Washington School of Medicine, Seattle 98195.

出版信息

J Clin Microbiol. 1989 Oct;27(10):2240-4. doi: 10.1128/jcm.27.10.2240-2244.1989.

DOI:10.1128/jcm.27.10.2240-2244.1989
PMID:2584375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267002/
Abstract

Seventy-five patients attending a clinic for chronic prostatitis were evaluated by use of lower urinary tract localization cultures. Coagulase-negative staphylococci, alpha-hemolytic streptococci, and diphtheroids were the most common isolates, but none of these organisms were pathogens, based on the absence of bacteriuria or evidence of an inflammatory response in prostatic secretions. Recognized uropathogens were isolated in 12 (16%) of the 75 cases and included Escherichia coli in 6 cases, Enterococcus spp. in 2 cases, and Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter cloacae, and Staphylococcus saprophyticus in 1 case each. Laboratory evaluation of men with chronic prostatitis should concentrate on the isolation and antimicrobial susceptibility testing of bacteria that have an established pathogenic potential in the genitourinary tract.

摘要

对75名前往慢性前列腺炎门诊的患者进行了下尿路定位培养评估。凝固酶阴性葡萄球菌、α溶血性链球菌和类白喉杆菌是最常见的分离菌,但基于无细菌尿或前列腺分泌物中无炎症反应证据,这些微生物均不是病原体。在75例病例中有12例(16%)分离出了公认的尿路病原体,其中6例为大肠杆菌,2例为肠球菌属,肺炎克雷伯菌、铜绿假单胞菌、阴沟肠杆菌和腐生葡萄球菌各1例。对慢性前列腺炎男性患者的实验室评估应集中于分离和检测对泌尿生殖道有确定致病潜力的细菌的抗菌药敏情况。

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引用本文的文献

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versus common uropathogens as a cause of chronic bacterial prostatitis: Is there any difference? Results of a prospective parallel-cohort study.对比常见尿路病原体作为慢性细菌性前列腺炎的病因:是否存在差异?一项前瞻性平行队列研究的结果。
Investig Clin Urol. 2017 Nov;58(6):460-467. doi: 10.4111/icu.2017.58.6.460. Epub 2017 Oct 31.
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The NIH Consensus concept of chronic prostatitis/chronic pelvic pain syndrome compared with traditional concepts of nonbacterial prostatitis and prostatodynia.美国国立卫生研究院(NIH)关于慢性前列腺炎/慢性盆腔疼痛综合征的共识概念与非细菌性前列腺炎和前列腺痛的传统概念的比较。
Curr Urol Rep. 2002 Aug;3(4):301-6. doi: 10.1007/s11934-002-0054-z.
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Outcome of antibiotic therapy with ciprofloxacin in chronic bacterial prostatitis.环丙沙星治疗慢性细菌性前列腺炎的疗效
Drugs. 1999;58 Suppl 2:103-6. doi: 10.2165/00003495-199958002-00021.
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Prokaryotic DNA sequences in patients with chronic idiopathic prostatitis.慢性特发性前列腺炎患者的原核生物DNA序列
J Clin Microbiol. 1996 Dec;34(12):3120-8. doi: 10.1128/jcm.34.12.3120-3128.1996.
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Update on clinical significance of coagulase-negative staphylococci.凝固酶阴性葡萄球菌临床意义的最新进展
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The diagnosis of prostatitis: a review.前列腺炎的诊断:综述
Genitourin Med. 1991 Aug;67(4):279-83. doi: 10.1136/sti.67.4.279.

本文引用的文献

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Canine prostatic secretions kill Trichomonas vaginalis.犬前列腺分泌物可杀死阴道毛滴虫。
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5
Difficulties in quantitating the contribution of urethral bacteria to prostatic fluid and seminal fluid cultures.定量尿道细菌对前列腺液和精液培养物的贡献存在困难。
J Urol. 1984 Sep;132(3):471-3. doi: 10.1016/s0022-5347(17)49695-9.
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Effect of seminal plasma on Chlamydia trachomatis strain LB-1 in cell culture.精浆对沙眼衣原体LB-1菌株在细胞培养中的影响。
Infect Immun. 1981 Apr;32(1):404-6. doi: 10.1128/iai.32.1.404-406.1981.
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Bacteriologic localization patterns in bacterial prostatitis and urethritis.细菌性前列腺炎和尿道炎中的细菌定位模式。
Invest Urol. 1968 Mar;5(5):492-518.
9
Antibacterial nature of prostatic fluid.前列腺液的抗菌特性。
Nature. 1968 May 4;218(5140):444-7. doi: 10.1038/218444a0.
10
The role of transurethral prostatectomy in chronic prostatitis.经尿道前列腺切除术在慢性前列腺炎中的作用。
Br J Urol. 1973 Dec;45(6):654-62. doi: 10.1111/j.1464-410x.1973.tb12236.x.