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Cloning and sequencing of the gene encoding the outer surface protein A (OspA) of a European Borrelia burgdorferi isolate.一株欧洲伯氏疏螺旋体分离株外表面蛋白A（OspA）编码基因的克隆与测序
Nucleic Acids Res. 1989 Nov 11;17(21):8864. doi: 10.1093/nar/17.21.8864.
2
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Use of the "blue halo" assay in the identification of genes encoding exported proteins with cleavable signal peptides: cloning of a Borrelia burgdorferi plasmid gene with a signal peptide.“蓝色晕圈”分析法在鉴定编码具有可切割信号肽的输出蛋白的基因中的应用：克隆带有信号肽的伯氏疏螺旋体质粒基因
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Expression and secretion of outer surface protein (OSP-A) of Borrelia burgdorferi from Escherichia coli.来自大肠杆菌的伯氏疏螺旋体外表面蛋白（OSP-A）的表达与分泌
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Protective immunization with plasmid DNA containing the outer surface lipoprotein A gene of Borrelia burgdorferi is independent of an eukaryotic promoter.用含有伯氏疏螺旋体外表面脂蛋白A基因的质粒DNA进行保护性免疫接种不依赖于真核启动子。
Eur J Immunol. 1996 Dec;26(12):2831-40. doi: 10.1002/eji.1830261206.

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Borrelia burgdorferi induces secretion of pro-urokinase-type plasminogen activator by human monocytes.伯氏疏螺旋体可诱导人单核细胞分泌尿激酶型纤溶酶原激活物前体。
Infect Immun. 1996 Oct;64(10):4307-12. doi: 10.1128/iai.64.10.4307-4312.1996.
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The recombinant outer surface protein A (lipOspA) of Borrelia burgdorferi: a Lyme disease vaccine.
Infection. 1996 Sep-Oct;24(5):396-7. doi: 10.1007/BF01716093.
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J Clin Microbiol. 1993 Feb;31(2):340-50. doi: 10.1128/jcm.31.2.340-350.1993.
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Borrelia burgdorferi is clonal: implications for taxonomy and vaccine development.伯氏疏螺旋体是克隆性的：对分类学和疫苗开发的影响。
Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10163-7. doi: 10.1073/pnas.90.21.10163.
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Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A.伯氏疏螺旋体通过蜱虫传播给近交系小鼠后，会诱导机体产生针对P39的抗体反应，但不会产生针对外表面蛋白A的抗体反应。
Infect Immun. 1994 Jun;62(6):2625-7. doi: 10.1128/iai.62.6.2625-2627.1994.
7
Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi.伯氏疏螺旋体一种新型多态性脂蛋白的分子与免疫特性
Infect Immun. 1993 Oct;61(10):4158-66. doi: 10.1128/iai.61.10.4158-4166.1993.
8
Detection of Borrelia burgdorferi sensu lato in lesional skin of patients with erythema migrans and acrodermatitis chronica atrophicans by ospA-specific PCR.通过ospA特异性PCR检测莱姆病红斑游走症和慢性萎缩性肢端皮炎患者皮损中的伯氏疏螺旋体狭义种。
J Clin Microbiol. 1994 Dec;32(12):2980-8. doi: 10.1128/jcm.32.12.2980-2988.1994.
9
The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor.疏螺旋体伯氏疏螺旋体的外表面蛋白A是一种纤溶酶（原）受体。
Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12594-8. doi: 10.1073/pnas.91.26.12594.
10
Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo.仅在体内表达的伯氏疏螺旋体新型线性质粒编码基因pG的分子克隆与免疫特性分析
Infect Immun. 1995 Sep;63(9):3327-35. doi: 10.1128/iai.63.9.3327-3335.1995.

本文引用的文献

1
A single recombinant plasmid expressing two major outer surface proteins of the Lyme disease spirochete.一种表达莱姆病螺旋体两种主要外表面蛋白的重组质粒。
Science. 1985 Feb 8;227(4687):645-6. doi: 10.1126/science.3969554.
2
Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit.莱姆病病原体伯氏疏螺旋体的两种外膜蛋白的编码基因在单个转录单元中的组织方式。
Infect Immun. 1986 Oct;54(1):207-12. doi: 10.1128/iai.54.1.207-212.1986.
3
Antigenic variability of Borrelia burgdorferi.伯氏疏螺旋体的抗原变异性
Ann N Y Acad Sci. 1988;539:126-43. doi: 10.1111/j.1749-6632.1988.tb31846.x.

Cloning and sequencing of the gene encoding the outer surface protein A (OspA) of a European Borrelia burgdorferi isolate.

作者信息

Wallich R, Schaible U E, Simon M M, Heiberger A, Kramer M D

机构信息

Department of Applied Immunology, German Cancer Research Center, (DKFZ), Heidelberg, FRG.

出版信息

Nucleic Acids Res. 1989 Nov 11;17(21):8864. doi: 10.1093/nar/17.21.8864.

DOI:10.1093/nar/17.21.8864
PMID:2587225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC335057/
Abstract
摘要