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功能性(心理性)运动障碍的表型特异性诊断

Phenotype-specific diagnosis of functional (psychogenic) movement disorders.

作者信息

Espay Alberto J, Lang Anthony E

机构信息

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA,

出版信息

Curr Neurol Neurosci Rep. 2015 Jun;15(6):32. doi: 10.1007/s11910-015-0556-y.

Abstract

Published diagnostic criteria for functional (psychogenic) movement disorders (FMDs) include psychiatric symptoms and some historical variables to affect the threshold between categories of diagnostic certainty. Clinically probable and possible categories, however, do not suffice to rule in FMD or rule out complex organic movement disorders and therefore are of little practical help. In contrast, a handful of unequivocal and reliably incongruent or inconsistent clinical features in each functional movement phenotype, when present, allow a clinically definite diagnosis of FMD, regardless of any psychiatric symptom. We suggest that the use of phenotype-specific clinically definite FMD diagnostic criteria will increase inter-rater reliability and minimize false-positive diagnostic errors. This process involves the ascertainment of core (mandatory) examination features instead of supportive but insufficiently sensitive historical, psychiatric, and inconsistent examination features.

摘要

已发布的功能性(心因性)运动障碍(FMDs)诊断标准包括精神症状和一些病史变量,以影响诊断确定性类别的阈值。然而,临床可能和疑似类别不足以确诊FMD或排除复杂的器质性运动障碍,因此实际帮助不大。相比之下,每种功能性运动表型中若存在一些明确且可靠的不一致或不相符的临床特征,则无论有无精神症状,均可做出FMD的临床确诊诊断。我们建议使用特定表型的FMD临床确诊诊断标准将提高评分者间的可靠性,并最大限度地减少假阳性诊断错误。这个过程涉及确定核心(强制性)检查特征,而不是支持性但敏感性不足的病史、精神症状和不一致的检查特征。

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