Abbas Zahid Khorshid, Saggu Shalini, Sakeran Mohamed I, Zidan Nahla, Rehman Hasibur, Ansari Abid A
Department of Biology, Faculty of Sciences, University of Tabuk, Tabuk 71491, Saudi Arabia.
Department of Chemistry, Faculty of Sciences, Tanta University, Tanta 31527, Egypt ; Department of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk 71491, Saudi Arabia.
Saudi J Biol Sci. 2015 May;22(3):322-6. doi: 10.1016/j.sjbs.2014.11.015. Epub 2014 Nov 20.
The phytochemical, antioxidant and mineral composition of hydroalcoholic extract of leaves of Cichorium intybus L., was determined. The leaves were found to possess comparatively higher values of total flavonoids, total phenolic acids. The phytochemical screening confirmed the presence of tannins, saponins, flavonoids, in the leaves of the plant. The leaf extract was found to show comparatively low value of IC50 for 2,2-diphenyl-1-picrylhydrazyl (DPPH) inhibition. The IC50 value of chicory leaves extract was found to be 67.2 ± 2.6 μg/ml. The extracts were found to contain high amount of mineral elements especially Mg and Zn. Due to good phytochemical and antioxidant composition, C. intybus L., leaves would be an important candidate in pharmaceutical formulations and play an important role in improving the human health by participating in the antioxidant defense system against free radical generation.
测定了菊苣叶水醇提取物的植物化学成分、抗氧化剂和矿物质组成。发现叶片中总黄酮、总酚酸含量相对较高。植物化学筛选证实该植物叶片中存在单宁、皂苷、黄酮类化合物。发现叶提取物对2,2-二苯基-1-苦基肼（DPPH）抑制的IC50值相对较低。菊苣叶提取物的IC50值为67.2±2.6μg/ml。发现提取物含有大量的矿物质元素，尤其是镁和锌。由于良好的植物化学成分和抗氧化成分，菊苣叶将成为药物制剂中的重要候选物，并通过参与抗氧化防御系统对抗自由基生成，在改善人类健康方面发挥重要作用。
