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韩国社会经济和生活方式因素与白内障的关系:2008 - 2011年韩国国家健康与营养检查调查

Relationship between socioeconomic and lifestyle factors and cataracts in Koreans: the Korea National Health and Nutrition Examination Survey 2008-2011.

作者信息

Nam G E, Han K, Ha S G, Han B-D, Kim D H, Kim Y-H, Cho K H, Park Y G, Ko B-J

机构信息

Department of Family Medicine, College of Medicine, Korea University, Seoul, South Korea.

Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

出版信息

Eye (Lond). 2015 Jul;29(7):913-20. doi: 10.1038/eye.2015.66. Epub 2015 May 15.

Abstract

PURPOSE

Cataracts are the leading cause of visual impairment and blindness, and therefore early identification and modification of the risk factors for cataracts are meaningful. This study aimed to investigate the relationship between socioeconomic status (SES) and lifestyle factors, and age-related cataracts in South Korea.

METHODS

This cross-sectional study was based on data collected in the 2008-2011 Korea National Health and Nutrition Examination Survey. A total of 15 866 subjects, aged ≥40 years, were included. SES was defined using household income and education level. Sociodemographic, lifestyle, and other associated factors were assessed by health interviews and examinations. Cataracts were diagnosed via slit-lamp examination using the Lens Opacities Classification System III.

RESULTS

The prevalence of any cataract was 38.9% in men and 42.3% in women (P<0.001). In women, the risk of cataracts increased with decreases in household income (P-value for trend=0.016 and 0.041 in any, and cortical cataract, respectively) and education level (P-value for trend=0.009, 0.027, and 0.016 in any, nuclear, and cortical cataract, respectively) after adjusting for confounding factors. Current smoking was correlated with nuclear cataracts in men (OR 1.21; 95% CI: 1.00, 1.46 in age-adjusted analysis) and cataract surgery in women (OR 2.25; 95% CI: 1.00, 5.04 in multivariate-adjusted analysis).

CONCLUSIONS

Socioeconomic disparities in cataract prevalence were observed in women; current smoking increased the risk of nuclear cataracts in men and surgery in women. Public health interventions focusing on gender differences are warranted to prevent and treat cataracts.

摘要

目的

白内障是视力损害和失明的主要原因,因此早期识别和改变白内障的危险因素具有重要意义。本研究旨在调查韩国社会经济地位(SES)、生活方式因素与年龄相关性白内障之间的关系。

方法

本横断面研究基于2008 - 2011年韩国国家健康与营养检查调查收集的数据。共纳入15866名年龄≥40岁的受试者。SES通过家庭收入和教育水平来定义。通过健康访谈和检查评估社会人口统计学、生活方式及其他相关因素。使用晶状体混浊分类系统III通过裂隙灯检查诊断白内障。

结果

男性任何类型白内障的患病率为38.9%,女性为42.3%(P<0.001)。在女性中,调整混杂因素后,白内障风险随家庭收入降低而增加(任何类型白内障和皮质性白内障的趋势P值分别为0.016和0.041),且随教育水平降低而增加(任何类型、核性和皮质性白内障的趋势P值分别为0.009、0.027和0.016)。当前吸烟与男性核性白内障相关(年龄调整分析中OR 1.21;95%CI:1.00,1.46)以及女性白内障手术相关(多变量调整分析中OR 2.25;95%CI:1.00,5.04)。

结论

在女性中观察到白内障患病率存在社会经济差异;当前吸烟增加男性患核性白内障及女性进行白内障手术的风险。有必要针对性别差异开展公共卫生干预措施以预防和治疗白内障。

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