Marneros A, Rohde A, Deister A
Psychiatric Department, University of Bonn, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1989;239(3):164-70. doi: 10.1007/BF01739649.
Seventy-two schizoaffective patients were investigated longitudinally (mean follow-up period 25.6 years). Of these, 37 were classified as unipolar and 35 as bipolar schizoaffectives. Their long-term courses were compared. Bipolar schizoaffectives were found to have shorter cycles, i.e. more frequent relapses and more episodes. Bipolars displayed much more variation in symptomatology. Unipolar schizo-affectives had longer periods of remission (that is the last relapse-free period if longer than 3 years) and more frequently showed suicidal symptomatology than did bipolar schizoaffectives. Altogether bipolar schizoaffective disorders had a more unfavourable course than unipolar disorders.
对72例分裂情感性障碍患者进行了纵向研究（平均随访期25.6年）。其中，37例被归类为单相型，35例为双相型分裂情感性障碍。比较了他们的长期病程。发现双相型分裂情感性障碍的发作周期较短，即复发更频繁且发作次数更多。双相型患者的症状表现变化更大。单相型分裂情感性障碍患者的缓解期更长（即最后一次无复发期超过3年），且比双相型分裂情感性障碍患者更频繁地出现自杀症状。总体而言，双相型分裂情感性障碍的病程比单相型障碍更差。
