Marneros A, Rohde A, Deister A, Fimmers R, Jünemann H
Psychiatric Department, University of Bonn, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1988;237(5):283-90. doi: 10.1007/BF00450547.
In addition to the findings presented previously, one-half of the 72 investigated schizoaffective patients had an acute onset. Onset of manic symptomatology was found to be usually acute. Although precipitating factors were found in 76% of the patients, this was found for only one-third of the 397 episodes. In spite of the fact that the majority of patients (61%) had a polymorphous course (with more than one type of episode), the pure schizophrenic or pure affective syndromes only seldomly dominated the course, as schizoaffectivity score and syndrome-presence index showed. Some 81% of the patients had delusions or hallucinations but only 37% of the individual episodes; 65% of the patients had suicidal symptomatology (24% of the episodes, mainly the schizodepressive ones). No seasonality was found, and 50% of the patients had a favorable outcome, only 6% ended in severe residuum. In old age the illness usually became inactive.
除了之前呈现的研究结果外，在72例接受调查的分裂情感性障碍患者中，有一半起病急骤。躁狂症状的发作通常较为急性。尽管76%的患者存在促发因素，但在397次发作中，只有三分之一的发作存在促发因素。尽管大多数患者（61%）病程呈多形性（有不止一种发作类型），但正如分裂情感性障碍评分和综合征存在指数所示，单纯的精神分裂症或单纯的情感综合征很少主导病程。约81%的患者有妄想或幻觉，但仅37%的个体发作有此症状；65%的患者有自杀症状（24%的发作有此症状，主要是分裂抑郁发作）。未发现季节性，50%的患者预后良好，只有6%的患者结局为严重残留症状。在老年时，病情通常不再活动。
