Marneros A, Rohde A, Deister A, Jünemann H, Fimmers R
Psychiatric Department, University of Bonn, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1988;237(5):276-82. doi: 10.1007/BF00450546.
Length of cycles, intervals, and episodes of 72 schizoaffective patients were investigated (duration of the follow-up means = 25.6 years, minimum 10, maximum 59 years). The average cycle length (time between beginning of an episode and next relapse) was found to be 37.5 months (median). Patients with a schizodepressive initial episode, unipolar course, and without precipitating factors relapsed much later than patients with schizomanic onset, bipolar course, and precipitating factors. The older the patient at onset the shorter the first cycle. The length of cycle decreased with increasing cycle number. Patients with schizodepressive onset, asthenic personality, and monomorphous course stayed in hospital longer or needed longer inpatient-like treatment than others. Length of cycles and intervals were characterized by an extraordinary intraindividual and interindividual variation.
对72例分裂情感性障碍患者的发作周期、发作间期及发作次数进行了调查（随访平均时长=25.6年，最短10年，最长59年）。发现平均发作周期长度（一次发作开始至下次复发的时间）为37.5个月（中位数）。首发为分裂抑郁发作、单相病程且无诱发因素的患者，其复发时间比首发为分裂躁狂发作、双相病程且有诱发因素的患者晚得多。发病时年龄越大，首个发作周期越短。发作周期长度随发作次数增加而缩短。首发为分裂抑郁发作、有虚弱型人格及单相病程的患者，其住院时间比其他患者更长，或需要更长时间的类似住院治疗。发作周期和发作间期的长度具有显著的个体内和个体间差异。
