Dogan Berna, Erol Muhammet Kazim, Toslak Devrim, Coban Deniz Turgut, Bulut Mehmet, Cengiz Ayse, Sari Esin Sogutlu
Antalya Training and Research Hospital, Eye Clinic, Antalya, Turkey.
Balıkesir University Medicine Faculty, Eye Clinic, Balıkesir, Turkey.
Ther Clin Risk Manag. 2015 Apr 30;11:683-9. doi: 10.2147/TCRM.S79232. eCollection 2015.
Bone marrow-derived multiple myeloma is a type of plasma cell tumor that may be associated with ocular complications. A 52-year-old male patient was admitted to our eye clinic with the complaint of sudden visual loss and a visual acuity of 20/50 in the right eye and 20/800 in the left eye. Fundus examination revealed common flame-shaped hemorrhages, venous dilatation and tortuosity, Roth spots, serous macular detachment, and yellow macular deposits in both eyes. Evaluation with fundus fluorescein angiography, fundus autofluorescence, and spectral-domain optical coherence tomography resulted in suspicion of hyperviscosity retinopathy and referral to the hematology clinic. After hematology consultation confirmed a diagnosis of multiple myeloma, chemotherapy and plasmapheresis were initiated. Four months after presentation, best-corrected visual acuity was 20/20 in both eyes and improvement in hyperviscosity retinopathy, serous macular detachment, and yellow macular deposits was observed.
骨髓源性多发性骨髓瘤是一种可能伴有眼部并发症的浆细胞肿瘤。一名52岁男性患者因突发视力丧失入院至我们的眼科门诊，右眼视力为20/50，左眼视力为20/800。眼底检查发现双眼均有常见的火焰状出血、静脉扩张迂曲、 Roth斑、浆液性黄斑脱离和黄斑黄色沉积物。通过眼底荧光血管造影、眼底自发荧光和光谱域光学相干断层扫描进行评估后，怀疑为高黏滞血症视网膜病变，并转诊至血液科门诊。血液科会诊确诊为多发性骨髓瘤后，开始进行化疗和血浆置换。就诊四个月后，双眼最佳矫正视力均为20/20，高黏滞血症视网膜病变、浆液性黄斑脱离和黄斑黄色沉积物均有改善。
