Ishag Osama M, Saeed Intisar K, Ali Yahia H
Rabak Veterinary Research Laboratory, White Nile state.
Onderstepoort J Vet Res. 2015 Aug 21;82(1):E1-4. doi: 10.4102/ojvr.v82i1.897.
Eight outbreaks of peste des petits ruminants in sheep and goats were reported in White Nile State, Sudan, between 2008 and 2009. A mortality rate of 4.2% was reported across the different outbreaks. Clinically the disease was characterised by high fever, ocular and nasal discharge, pneumonia, ulceration of the mucous membranes, diarrhoea and death. The postmortem findings included necrotic lesions in the mouth and gastrointestinal tract, and swollen, oedematous lymph nodes associated with the lungs and intestine. Of the 209 serum samples tested by competitive enzyme-linked immunosorbent assay, 113 (54%) were found positive. Peste des petits ruminants virus was confirmed in tissues, nasal swabs and blood samples by immunocapture enzyme-linked immunosorbent assay, reverse-transcription polymerase chain reaction and isolation of the virus in culture of lamb testicle cells.
2008年至2009年期间,苏丹白尼罗河州报告了8起绵羊和山羊小反刍兽疫疫情。不同疫情的死亡率报告为4.2%。临床上,该病的特征为高热、眼鼻分泌物、肺炎、黏膜溃疡、腹泻和死亡。尸检结果包括口腔和胃肠道的坏死性病变,以及与肺和肠道相关的肿胀、水肿的淋巴结。通过竞争性酶联免疫吸附试验检测的209份血清样本中,有113份(54%)呈阳性。通过免疫捕获酶联免疫吸附试验、逆转录聚合酶链反应以及在羔羊睾丸细胞培养物中分离病毒,在组织、鼻拭子和血液样本中确认了小反刍兽疫病毒。