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马流感疫苗接种最新进展的系统评价

A Systematic Review of Recent Advances in Equine Influenza Vaccination.

作者信息

Paillot Romain

机构信息

Animal Health Trust, Centre for Preventive Medicine, Lanwades Park, Newmarket, Suffolk CB8 7UU, UK.

出版信息

Vaccines (Basel). 2014 Nov 14;2(4):797-831. doi: 10.3390/vaccines2040797.

DOI:10.3390/vaccines2040797
PMID:26344892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4494246/
Abstract

Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strategies of vaccination are also evaluated. This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

摘要

马流感（EI）是马匹的一种主要呼吸道疾病，尽管经过数十年的监测和预防，仍在全球范围内引发大量疫情。除检疫程序外，疫苗接种被广泛用于预防或限制疾病传播。市面上可获得的EI疫苗种类可能是最多样化的之一，包括全病毒灭活疫苗、免疫刺激复合物佐剂疫苗（免疫刺激复合物和免疫刺激复合物基质）、一种减毒活马流感病毒（EIV）疫苗和一种重组痘病毒载体疫苗。其他几种疫苗接种策略也在评估中。本系统综述报告了过去几年EI疫苗的进展以及马匹对疫苗接种反应低效或不理想背后的一些机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/b7a02376e33b/vaccines-02-00797-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/b7a02376e33b/vaccines-02-00797-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/fbd5064bf1df/vaccines-02-00797-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/adedb894aec8/vaccines-02-00797-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/80837b98cda5/vaccines-02-00797-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e405/4494246/b7a02376e33b/vaccines-02-00797-g005.jpg

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本文引用的文献

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Equine Vet J. 2014 Nov;46(6):669-73. doi: 10.1111/evj.12214. Epub 2014 Jan 29.
2
The evaluation of a nucleoprotein ELISA for the detection of equine influenza antibodies and the differentiation of infected from vaccinated horses (DIVA).用于检测马流感抗体的核蛋白 ELISA 的评估以及区分感染和接种疫苗的马（DIVA）。
Influenza Other Respir Viruses. 2013 Dec;7 Suppl 4(Suppl 4):73-80. doi: 10.1111/irv.12195.
3
Epidemiological and virological investigations of equine influenza outbreaks in Ireland (2010-2012).
灭活羊副痘病毒对马流感加强免疫血清学反应的免疫刺激作用
Vaccines (Basel). 2022 Dec 14;10(12):2139. doi: 10.3390/vaccines10122139.
4
Equine Influenza Virus: An Old Known Enemy in the Americas.马流感病毒：美洲的一个老对手。
Vaccines (Basel). 2022 Oct 14;10(10):1718. doi: 10.3390/vaccines10101718.
5
An epidemiological overview of the equine influenza epidemic in Great Britain during 2019.2019 年英国马流感疫情的流行病学概述。
Equine Vet J. 2023 Jan;55(1):153-164. doi: 10.1111/evj.13874. Epub 2022 Aug 31.
6
A Review on Equine Influenza from a Human Influenza Perspective.从人类流感角度看马流感综述。
Viruses. 2022 Jun 15;14(6):1312. doi: 10.3390/v14061312.
7
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爱尔兰马流感疫情（2010-2012 年）的流行病学和病毒学调查。
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5
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9
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