Bisschop M P, Merkus J M, Scheygrond H, Van Cutsem J, van de Kuy A
Eur J Obstet Gynecol Reprod Biol. 1979 Aug;9(4):253-9. doi: 10.1016/0028-2243(79)90065-0.
The efficacy of a new, orally active antimycotic, ketoconazole, in the treatment of vaginal candidiasis was studied at different doses involving 63 patients. All patients had subjective complaints and were mycologically positive. There was no significant difference in the cure rates of the different doses. The oral treatment was successful in 55 out of 63 patients (87.3%). No correlation was found between the relapse rate of vaginal candidiasis and the dose regimen. There were no serious side-effects, and no significant changes were reported in hematological and biochemical parameters.
对一种新型口服抗真菌药酮康唑治疗阴道念珠菌病的疗效进行了研究，涉及63例患者，采用了不同剂量。所有患者均有主观症状且真菌学检查呈阳性。不同剂量的治愈率无显著差异。63例患者中有55例（87.3%）口服治疗成功。未发现阴道念珠菌病的复发率与给药方案之间存在相关性。未出现严重副作用，血液学和生化参数也未报告有显著变化。
