Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Victoria, Australia.
The Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.
Nat Methods. 2015 Oct;12(10):917-9. doi: 10.1038/nmeth.3586.
Recent studies show that pluripotent stem cells can undergo self-organized development in vitro into structures that mimic the body plan of the post-implantation embryo. Modeling human embryogenesis in a dish opens up new possibilities for the study of early development and developmental disorders, but it may also raise substantial ethical concerns.
最近的研究表明,多能干细胞可以在体外进行自我组织发育,形成模拟胚胎植入后体节的结构。在培养皿中模拟人类胚胎发生为早期发育和发育障碍的研究开辟了新的可能性,但也可能引起重大的伦理问题。