Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genova, Italy.
Adv Mater. 2015 Nov 25;27(44):7145-9. doi: 10.1002/adma.201503252. Epub 2015 Oct 7.
A Universal plasmonic/microfluidic platform for spatial and temporal controlled intracellular delivery is described. The system can inject/transfect the desired amount of molecules with an efficacy close to 100%. Moreover, it is highly scalable from single cells to large ensembles without administering the molecules to an extracellular bath. The latter enables quantitative control over the amount of injected molecules.
本文描述了一种通用的等离子体/微流控平台，用于实现时空控制的细胞内递药。该系统可以将所需量的分子以接近 100%的效率注入/转染。此外，该系统具有高度的可扩展性，从单细胞到大型细胞群体均可，而无需将分子递送到细胞外浴中。后者可以实现对注入分子数量的定量控制。
