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中国东部城乡女性乳腺癌的危险因素。

Risk factors for breast cancer in women residing in urban and rural areas of eastern China.

作者信息

Wang Feng, Yu LiXiang, Wang Fei, Liu LiYuan, Guo MingMing, Gao DeZong, Zhang Qiang, Li YuYang, Li Liang, Fu QinYe, Yu ZhiGang

机构信息

Department of Breast Diseases, Second Hospital of Shandong University, Jinan, Shandong, China.

Epidemiology Institute, School of Public Health, Shandong University, Jinan, Shandong, China.

出版信息

J Int Med Res. 2015 Dec;43(6):774-89. doi: 10.1177/0300060515592901. Epub 2015 Oct 16.

DOI:10.1177/0300060515592901
PMID:26475794
Abstract

OBJECTIVE

To investigate breast cancer risk factors in Chinese women residing in urban and rural areas of eastern China using a large-scale cross-sectional survey.

METHODS

In this multistage, stratified cluster sampling epidemiological survey, information on demographic characteristics, diet and lifestyle variables were gathered using a carefully designed questionnaire. Multivariate logistic regression analysis and subgroup analyses of the data were performed, including separate analyses of data from women residing in urban and rural areas.

RESULTS

A total of 122,058 women were included in the survey. Age, body mass index, number of miscarriages, family history of breast cancer and menopausal status were found to be risk factors for breast cancer, while the consumption of soya bean products was a protective factor. Among women residing in urban areas, high or moderate intake of soya bean products and red meat were protective factors. Among women residing in rural areas, obesity and a high intake of milk were identified as risk factors for breast cancer, while a moderate intake of soya bean products was a protective factor.

CONCLUSIONS

This type of data is crucial for understanding the risk factors for breast cancer and could facilitate the development and targeting of effective intervention strategies, with the ultimate aim of breast cancer prevention.

摘要

目的

通过大规模横断面调查,研究中国东部城乡地区女性的乳腺癌风险因素。

方法

在这项多阶段、分层整群抽样的流行病学调查中,使用精心设计的问卷收集人口统计学特征、饮食和生活方式变量等信息。对数据进行多因素逻辑回归分析和亚组分析,包括对城乡女性数据的单独分析。

结果

共有122,058名女性纳入调查。年龄、体重指数、流产次数、乳腺癌家族史和绝经状态被发现是乳腺癌的风险因素,而食用豆制品是一个保护因素。在城市女性中,高或中等摄入量的豆制品和红肉是保护因素。在农村女性中,肥胖和高牛奶摄入量被确定为乳腺癌的风险因素,而中等摄入量的豆制品是保护因素。

结论

这类数据对于了解乳腺癌风险因素至关重要,有助于制定和靶向有效的干预策略,最终目标是预防乳腺癌。

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