Garcia-Feijoo Julian, Martinez-de-la-Casa Jose María, Morales-Fernandez Laura, Saenz Frances Federico, Santos-Bueso Enrique, Garcia-Saenz Sofia, Mendez-Hernandez Carmen
Servicio de Oftalmología, Hospital Clínico San Carlos, Departamento de Oftalmología y ORL, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality, Instituto de Salud Carlos III, Madrid, Spain.
Servicio de Oftalmología, Hospital Clínico San Carlos, Departamento de Oftalmología y ORL, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality, Instituto de Salud Carlos III, Madrid, Spain.
Prog Brain Res. 2015;221:67-79. doi: 10.1016/bs.pbr.2015.06.003. Epub 2015 Oct 1.
The level of intraocular pressure (IOP) is the main known risk factor for the development and progression of glaucomatous optic neuropathy. Despite Goldmann applanation tonometry (GAT) being the gold standard for determining IOP since the last century, its limitations were obvious from the start and include substantial effects of several eye variables such as axial length, curvature, rigidity, and corneal thickness. These limitations have prompted the development of numerous formulas and nomograms designed to compensate for the ocular characteristics effect on GAT, but none of these methods has been entirely satisfactory. Similarly, as a result of efforts to mitigate some of the limitations of conventional tonometry, several new tonometers have appeared on the scene.
眼压(IOP)水平是青光眼性视神经病变发生和进展的主要已知危险因素。尽管自上世纪以来,Goldmann压平眼压计(GAT)一直是测定眼压的金标准,但其局限性从一开始就很明显,包括眼轴长度、曲率、硬度和角膜厚度等多个眼部变量的显著影响。这些局限性促使人们开发了许多公式和列线图,旨在补偿眼部特征对GAT的影响,但这些方法都不完全令人满意。同样,由于努力减轻传统眼压测量法的一些局限性,一些新型眼压计应运而生。