Das Sneha, Vasudeva Neeru, Sharma Sunil
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, 125001, India.
Org Med Chem Lett. 2014 Dec;4(1):13. doi: 10.1186/s13588-014-0013-y. Epub 2014 Dec 2.
Macrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches. It is used in kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors. It is reported as an antioxidant and nutraceutical (forage and food). GC-MS analysis of ethanol extract has led to identification of twenty-eight compounds from M. uniflorum by comparison of their retention indices and mass spectra fragmentation patterns with those stored on the GC-MS computer library.
The main constituents identified were mome inositol, ethyl alpha-d-glucopyranoside, n- hexadecanoic acid, linoleic acid (9, 12-octadecadienoic acid), its esters and ethyl derivatives, Vitamin E, stigmasterol and 3-beta-stigmast-5-en-3-ol.
The extracts are rich in linoleic acid and its esters, mome inositol and ethyl alpha-d-glucopyranoside; therefore, this plant can be medicinally beneficial as an antioxidant, in diabetes and its related disorders.
单花大翼豆（豆科）是一种具有一年生枝条的草本植物。它用于治疗肾结石、关节发炎、发烧、肌肉骨骼疾病、鼻窦伤口和局部腹部肿瘤。据报道，它具有抗氧化剂和营养保健品（饲料和食品）的作用。通过将乙醇提取物的保留指数和质谱碎片模式与气相色谱-质谱计算机库中存储的模式进行比较，气相色谱-质谱分析已从单花大翼豆中鉴定出28种化合物。
鉴定出的主要成分是肌醇、α-D-葡萄糖吡喃苷乙酯、正十六烷酸、亚油酸（9,12-十八碳二烯酸）及其酯类和乙基衍生物、维生素E、豆甾醇和3-β-豆甾-5-烯-3-醇。
提取物富含亚油酸及其酯类、肌醇和α-D-葡萄糖吡喃苷乙酯；因此，这种植物作为抗氧化剂，在糖尿病及其相关疾病中可能具有药用价值。
