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玻璃体切除术及视网膜前膜剥除术治疗干性年龄相关性黄斑变性的疗效

Efficacy of vitrectomy and epiretinal membrane peeling in eyes with dry age-related macular degeneration.

作者信息

Mason John O, Patel Shyam A

机构信息

Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, AL, USA ; Retina Consultants of Alabama, Callahan Eye Foundation Hospital, Birmingham, AL, USA.

Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, AL, USA.

出版信息

Clin Ophthalmol. 2015 Oct 23;9:1999-2003. doi: 10.2147/OPTH.S94948. eCollection 2015.

DOI:10.2147/OPTH.S94948
PMID:26604669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4629981/
Abstract

OBJECTIVE

To study the efficacy of epiretinal membrane (ERM) peeling in eyes with dry age-related macular degeneration (AMD).

METHODS

We retrospectively analyzed patient charts on 17 eyes (16 patients) that underwent ERM peeling with a concurrent diagnosis of dry AMD.

RESULTS

Eyes with concurrent dry AMD and with a good preoperative best-corrected visual acuity (BCVA) (better than or equal to 20/50) had a statistically significant mean BCVA improvement at 6 months after ERM peeling. There was a statistical increase in mean BCVA from 20/95 to 20/56 in dry AMD eyes, and no eyes showed worsening in BCVA at 6 months or at most recent follow-up. Five/seventeen (29.4%) eyes had cataract formation or progression. There were no other complications, reoperations, or reoccurrences.

CONCLUSION

ERM peeling in eyes with dry AMD may show significant improvement, especially in eyes with good preoperative BCVA. The procedure is relatively safe with low complications and reoccurrences.

摘要

目的

研究视网膜前膜(ERM)剥除术治疗干性年龄相关性黄斑变性(AMD)的疗效。

方法

我们回顾性分析了17只眼(16例患者)的病历,这些患者在诊断为干性AMD的同时接受了ERM剥除术。

结果

术前最佳矫正视力(BCVA)良好(优于或等于20/50)的干性AMD患者,在ERM剥除术后6个月,平均BCVA有统计学意义的显著改善。干性AMD患者的平均BCVA从20/95提高到20/56,且在6个月或最近一次随访时,没有眼睛的BCVA恶化。17只眼中有5只(29.4%)出现白内障形成或进展。没有其他并发症、再次手术或复发情况。

结论

干性AMD患者行ERM剥除术可能会有显著改善,尤其是术前BCVA良好的患者。该手术相对安全,并发症和复发率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de88/4629981/0e6106556ef9/opth-9-1999Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de88/4629981/0e6106556ef9/opth-9-1999Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de88/4629981/0e6106556ef9/opth-9-1999Fig1.jpg

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2
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Retina. 2015 Sep;35(9):1822-7. doi: 10.1097/IAE.0000000000000541.
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Results and prognostic factors for visual improvement after pars plana vitrectomy for idiopathic epiretinal membrane.
特发性视网膜前膜玻璃体切除术后视力改善的结果及预后因素
Retina. 2015 May;35(5):866-72. doi: 10.1097/IAE.0000000000000406.
4
Contrast sensitivity and foveal microstructure following vitrectomy for epiretinal membrane.视网膜前膜玻璃体切除术后的对比敏感度和黄斑微结构
Invest Ophthalmol Vis Sci. 2014 Nov 4;55(11):7594-600. doi: 10.1167/iovs.14-14035.
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Early surgery for epiretinal membrane preserves more vision for patients.视网膜前膜早期手术可为患者保留更多视力。
Eye (Lond). 2014 Apr;28(4):410-4. doi: 10.1038/eye.2013.305. Epub 2014 Jan 10.
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Visual acuity outcomes following surgery for idiopathic epiretinal membrane: an analysis of data from 2001 to 2011.特发性视网膜前膜手术后的视力结果:对2001年至2011年数据的分析
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