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克服腹膜透析利用不足的问题

Overcoming the Underutilisation of Peritoneal Dialysis.

作者信息

Pajek Jernej

机构信息

Department of Nephrology, University Medical Centre Ljubljana, Zaloška 2, SI-1525 Ljubljana, Slovenia.

出版信息

Biomed Res Int. 2015;2015:431092. doi: 10.1155/2015/431092. Epub 2015 Nov 11.

Abstract

Peritoneal dialysis is troubled with declining utilisation as a form of renal replacement therapy in developed countries. We review key aspects of therapy evidenced to have a potential to increase its utilisation. The best evidence to repopulate PD programmes is provided for the positive impact of timely referral and systematic and motivational predialysis education: average odds ratio for instituting peritoneal dialysis versus haemodialysis was 2.6 across several retrospective studies on the impact of predialysis education. Utilisation of PD for unplanned acute dialysis starts facilitated by implantation of peritoneal catheters by interventional nephrologists may diminish the vast predominance of haemodialysis done by central venous catheters for unplanned dialysis start. Assisted peritoneal dialysis can improve accessibility of home based dialysis to elderly, frail, and dependant patients, whose quality of life on replacement therapy may benefit most from dialysis performed at home. Peritoneal dialysis providers should perform close monitoring, preventing measures, and timely prophylactic therapy in patients judged to be prone to EPS development. Each peritoneal dialysis programme should regularly monitor, report, and act on key quality indicators to manifest its ability of constant quality improvement and elevate the confidence of interested patients and financing bodies in the programme.

摘要

在发达国家,腹膜透析作为一种肾脏替代疗法,其使用率不断下降,面临困境。我们回顾了已证明有可能提高其使用率的治疗关键方面。及时转诊以及系统且具有激励性的透析前教育所产生的积极影响,为腹膜透析项目的重新发展提供了最佳证据:在多项关于透析前教育影响的回顾性研究中,开始腹膜透析与血液透析的平均优势比为2.6。介入肾脏病医生植入腹膜导管有助于非计划急性透析起始时使用腹膜透析,这可能会减少因非计划透析起始而通过中心静脉导管进行血液透析的巨大优势。辅助腹膜透析可以改善老年、体弱和依赖患者接受家庭透析的可及性,这些患者在替代治疗中的生活质量可能从在家中进行透析中获益最大。腹膜透析提供者应对被判定易于发生腹膜透析相关感染性腹膜炎(EPS)的患者进行密切监测、预防措施和及时的预防性治疗。每个腹膜透析项目都应定期监测、报告关键质量指标并据此采取行动,以展现其持续质量改进的能力,并提高感兴趣的患者和资助机构对该项目的信心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b7d/4658397/fa59068a73a7/BMRI2015-431092.001.jpg

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