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有氧运动间歇训练对缺血性心力衰竭合并植入式心脏复律除颤器患者焦虑、抑郁及生活质量指标的影响:一项前瞻性非随机试验。

Effects of aerobic interval training on measures of anxiety, depression and quality of life in patients with ischaemic heart failure and an implantable cardioverter defibrillator: A prospective non-randomized trial.

作者信息

Isaksen Kjetil, Munk Peter Scott, Giske Rune, Larsen Alf Inge

机构信息

Department of Cardiology, Stavanger University Hospital,. PO Box-box 8100, NO-4068 Stavanger, Norway.

出版信息

J Rehabil Med. 2016 Mar;48(3):300-6. doi: 10.2340/16501977-2043.

DOI:10.2340/16501977-2043
PMID:26667151
Abstract

OBJECTIVE

To evaluate the short- and long-term effects of aerobic interval training on quality of life and on symptoms of anxiety and depression among patients with ischaemic heart failure and an implantable cardioverter defibrillator.

DESIGN

Prospective, non-randomized controlled study.

SUBJECTS

Patients with ischaemic heart failure and an implantable cardioverter defibrillator, willing to undergo an aerobic interval training programme. A total of 31 patients were enrolled (19 were assigned to the aerobic interval training group and 12 to the control group).

METHODS

The aerobic interval training group performed a 12-week exercise training programme. All patients were evaluated with the Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale (HADS) and the International Physical Activity Questionnaire at baseline, after 12 weeks and at 2 years.

RESULTS

The aerobic interval training group showed significant improvements in several SF-36 subscores at 12 weeks. There was an unadjusted significant reduction in the HADS depression (HADS-D) score. At follow-up, results in the aero-bic interval training group moved towards baseline or remained stable, whereas in the control group HADS-D scores and some SF-36 subscores deteriorated.

CONCLUSION

Participation in a 12-week aerobic interval training programme resulted in significant improvements in several measures of quality of life and the unadjusted HADS-D score in patients with ischaemic heart failure with an implantable cardioverter defibrillator. At follow-up there was significantly less sedentary activity in the aerobic interval training group, while psychometric measures were no longer significantly different from baseline.

摘要

目的

评估有氧间歇训练对缺血性心力衰竭且植入了植入式心律转复除颤器患者的生活质量以及焦虑和抑郁症状的短期和长期影响。

设计

前瞻性、非随机对照研究。

研究对象

缺血性心力衰竭且植入了植入式心律转复除颤器、愿意接受有氧间歇训练计划的患者。共招募了31名患者(19名被分配到有氧间歇训练组,12名被分配到对照组)。

方法

有氧间歇训练组进行为期12周的运动训练计划。所有患者在基线、12周后和2年时使用简短健康调查问卷(SF-36)、医院焦虑抑郁量表(HADS)和国际体力活动问卷进行评估。

结果

有氧间歇训练组在12周时,SF-36的几个子评分有显著改善。HADS抑郁(HADS-D)评分未经调整有显著降低。在随访时,有氧间歇训练组的结果趋向于基线或保持稳定,而对照组的HADS-D评分和一些SF-36子评分恶化。

结论

参与为期12周的有氧间歇训练计划可使缺血性心力衰竭且植入了植入式心律转复除颤器的患者在生活质量的多项指标以及未经调整的HADS-D评分方面有显著改善。在随访时,有氧间歇训练组的久坐活动明显减少,而心理测量指标与基线不再有显著差异。

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