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宽视野模拟眼在光学相干断层扫描和反射成像中的应用。

Application of a wide-field phantom eye for optical coherence tomography and reflectance imaging.

作者信息

Corcoran Anthony, Muyo Gonzalo, van Hemert Jano, Gorman Alistair, Harvey Andrew R

机构信息

Physics and Astronomy Department, University of Glasgow , Glasgow , Scotland .

Research Department, Optos PLC , Dunfermline , Scotland .

出版信息

J Mod Opt. 2015 Dec 15;62(21):1828-1838. doi: 10.1080/09500340.2015.1045309. Epub 2015 Jun 23.

DOI:10.1080/09500340.2015.1045309
PMID:26740737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4685623/
Abstract

Optical coherence tomography (OCT) and reflectance imaging are used in clinical practice to measure the thickness and transverse dimensions of retinal features. The recent trend towards increasing the field of view (FOV) of these devices has led to an increasing significance of the optical aberrations of both the human eye and the device. We report the design, manufacture and application of the first phantom eye that reproduces the off-axis optical characteristics of the human eye, and allows the performance assessment of wide-field ophthalmic devices. We base our design and manufacture on the wide-field schematic eye, [Navarro, R. , .] as an accurate proxy to the human eye and enable assessment of ophthalmic imaging performance for a [Formula: see text] external FOV. We used multi-material 3D-printed retinal targets to assess imaging performance of the following ophthalmic instruments: the Optos 200Tx, Heidelberg Spectralis, Zeiss FF4 fundus camera and Optos and use the phantom to provide an insight into some of the challenges of wide-field OCT.

摘要

光学相干断层扫描（OCT）和反射成像在临床实践中用于测量视网膜特征的厚度和横向尺寸。这些设备扩大视野（FOV）的最新趋势使得人眼和设备的光学像差的重要性日益增加。我们报告了首个模拟眼的设计、制造和应用，该模拟眼可再现人眼的离轴光学特性，并能对广域眼科设备的性能进行评估。我们基于广域示意眼[纳瓦罗，R.，……]进行设计和制造，将其作为人眼的精确替代物，并能够评估[公式：见原文]外部视野下的眼科成像性能。我们使用多材料3D打印视网膜靶标来评估以下眼科仪器的成像性能：Optos 200Tx、海德堡光谱仪、蔡司FF4眼底相机和Optos，并利用该模拟眼深入了解广域OCT面临的一些挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/05564db2bf6c/tmop_a_1045309_f0012_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/24486b7a6301/tmop_a_1045309_f0001_oc.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/a49af7be5f98/tmop_a_1045309_f0005_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/eb8398caf336/tmop_a_1045309_f0006_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/a2c82da3890e/tmop_a_1045309_f0007_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/1926bf3d365c/tmop_a_1045309_f0008_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/c0f83425871e/tmop_a_1045309_f0009_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/ea9fd3d91b23/tmop_a_1045309_f0010_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/b6e5b85e5c5d/tmop_a_1045309_f0011_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/05564db2bf6c/tmop_a_1045309_f0012_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/24486b7a6301/tmop_a_1045309_f0001_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/c8e98a96e630/tmop_a_1045309_f0002_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/02fc355a0418/tmop_a_1045309_f0003_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/484e573124df/tmop_a_1045309_f0004_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/a49af7be5f98/tmop_a_1045309_f0005_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/eb8398caf336/tmop_a_1045309_f0006_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/a2c82da3890e/tmop_a_1045309_f0007_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/1926bf3d365c/tmop_a_1045309_f0008_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/c0f83425871e/tmop_a_1045309_f0009_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/ea9fd3d91b23/tmop_a_1045309_f0010_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/b6e5b85e5c5d/tmop_a_1045309_f0011_oc.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b328/4685623/05564db2bf6c/tmop_a_1045309_f0012_oc.jpg

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