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对来自南美国产猪的属于序列型(ST)410、ST224和ST1284的产CTX-M-15大肠杆菌菌株的首次鉴定。

First Characterization of CTX-M-15-Producing Escherichia coli Strains Belonging to Sequence Type (ST) 410, ST224, and ST1284 from Commercial Swine in South America.

作者信息

Silva Ketrin C, Moreno Marina, Cabrera Carlos, Spira Beny, Cerdeira Louise, Lincopan Nilton, Moreno Andrea M

机构信息

Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.

Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

出版信息

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2505-8. doi: 10.1128/AAC.02788-15. Print 2016 Apr.

Abstract

We report for the first time the isolation of CTX-M-15-producingEscherichia colistrains belonging to sequence type (ST) 410, ST224, and ST1284 in commercial swine in Brazil. TheblaCTX-M-15gene was located on F-::A9::B1 and C1::A9::B1 IncF-type plasmids, surrounded by a new genetic context comprising the IS26insertion sequence truncated with the ISEcp1element upstream ofblaCTX-M-15 These results reveal that commercial swine have become a new reservoir of CTX-M-15-producing bacteria in South America.

摘要

我们首次报告在巴西商业养猪场中分离出属于序列型(ST)410、ST224和ST1284的产CTX-M-15大肠杆菌菌株。blaCTX-M-15基因位于F-::A9::B1和C1::A9::B1 IncF型质粒上,其周围是一个新的基因环境,包括在blaCTX-M-15上游被ISEcp1元件截断的IS26插入序列。这些结果表明,商业养猪场已成为南美洲产CTX-M-15细菌的新储存库。

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