Kong Ling-Han, Lei Chang-Wei, Ma Su-Zhen, Jiang Wei, Liu Bi-Hui, Wang Yong-Xiang, Guan Ru, Men Shuai, Yuan Qi-Wu, Cheng Guang-Yang, Zhou Wen-Cheng, Wang Hong-Ning
College of Life Science, Sichuan University, Chengdu, People's Republic of China.
Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China.
Antimicrob Agents Chemother. 2017 Feb 23;61(3). doi: 10.1128/AAC.02167-16. Print 2017 Mar.
Sixteen different sequence types (STs) of isolates from a commercial swine farm in China were confirmed to coharbor the carbapenem resistance gene and the colistin resistance gene Whole-genome sequencing revealed that and were located on a 46-kb IncX3 plasmid and a 32-kb IncX4 plasmid, respectively. The two plasmids can transfer together with a low fitness cost, which might explain the presence of various STs of coharboring and .
在中国一个商业化养猪场分离出的菌株中,16种不同的序列类型(STs)被证实同时携带碳青霉烯抗性基因和黏菌素抗性基因。全基因组测序显示,它们分别位于一个46 kb的IncX3质粒和一个32 kb的IncX4质粒上。这两个质粒可以以较低的适应性代价一起转移,这可能解释了同时携带这两种抗性基因的不同STs的存在。