Erkut Adem, Tumkaya Levent, Balik Mehmet Sabri, Kalkan Yildiray, Guvercin Yilmaz, Yilmaz Adnan, Yuce Suleyman, Cure Erkan, Sehitoglu Ibrahim
School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
Department of Internal Medicine, Kumru State Hospital, Ordu, Turkey.
Acta Cir Bras. 2016 Feb;31(2):74-83. doi: 10.1590/S0102-865020160020000001.
To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats.
Pregnant rats in the experimental group were exposed to radiation for six, 12, and 24 hours daily for 20 days. No radiation was given to the pregnant rats in the control group. We distributed the newborn rats into four groups according to prenatal EMF exposure as follows: Group 1 was not exposed to EMF; groups 2, 3, and 4 were exposed to EMF for six, 12, and 24 hours a day, respectively. The rats were evaluated at the end of the 60th day following birth.
Increasing the duration of EMF exposure during the prenatal period resulted in a significant reduction of resting cartilage levels and a significant increase in the number of apoptotic chondrocytes and myocytes. There was also a reduction in calcineurin activities in both bone and muscle tissues. We observed that the development of the femur, tibia, and ulna were negatively affected, especially with a daily EMF exposure of 24 hours.
Bone and muscle tissue development was negatively affected due to prenatal exposure to 1800 MHz radiofrequency electromagnetic field.
研究暴露于1800兆赫电磁场（EMF）对大鼠孕期骨骼发育的影响。
实验组怀孕大鼠每天接受6、12和24小时的辐射，持续20天。对照组怀孕大鼠不接受辐射。我们根据产前EMF暴露情况将新生大鼠分为四组，如下：第1组未暴露于EMF；第2、3和4组分别每天暴露于EMF 6、12和24小时。在出生后第60天结束时对大鼠进行评估。
孕期增加EMF暴露时间导致静止软骨水平显著降低，凋亡软骨细胞和肌细胞数量显著增加。骨和肌肉组织中的钙调神经磷酸酶活性也降低。我们观察到股骨、胫骨和尺骨的发育受到负面影响，尤其是每天暴露于EMF 24小时的情况。
产前暴露于1800兆赫射频电磁场对骨和肌肉组织发育产生负面影响。
