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[早期神经科/神经外科康复中的康复进程。2014年德国多中心评估结果]

[Course of rehabilitation in early neurological/neurosurgical rehabilitation. Results of a 2014 multi-center evaluation in Germany].

作者信息

Pohl M, Bertram M, Bucka C, Hartwich M, Jöbges M, Ketter G, Leineweber B, Mertl-Rötzer M, Nowak D A, Platz T, Rollnik J D, Scheidtmann K, Thomas R, von Rosen F, Wallesch C W, Woldag H, Peschel P, Mehrholz J

机构信息

Helios Klinik Schloss Pulsnitz, Wittgensteiner Straße 1, 01896, Pulsnitz, Deutschland.

Klinik Bavaria Kreischa, Kreischa, Deutschland.

出版信息

Nervenarzt. 2016 Jun;87(6):634-44. doi: 10.1007/s00115-016-0093-1.

Abstract

BACKGROUND

In Germany, neurological-neurosurgical early rehabilitation is well established in the treatment of severe neurological diseases. To develop quality standards, knowledge of the current rehabilitation course is required.

PATIENTS AND METHODS

A retrospective analysis was performed on the course of rehabilitation from patients in an early neurological/neurosurgical rehabilitation program in 16 centers from 10 German states. The odds for a good or poor outcome were investigated using a multivariate logistic regression model.

RESULTS

Seven hundred and fifty-four patients were included in the study. The average age of the patients was 68 ± 15 years. Of the patients studied, 26 % were on mechanical ventilation commencing their neurological rehabilitation. The average duration of stay was 56 ± 51 days. Weaning rate from mechanical ventilation was 65 % and the rate of weaning from tracheal cannula was 54 %. Mean improvement in the Barthel Index of 17 points, significant reduction of dysphagia (from 62 to 30 %) and depended walking (from 99 to 82 %), and the achievement of phase C (the next stage of rehabilitation) in 38 % can still be counted as signs of successful rehabilitation. During their course of stay, near 10 % of the patients died. Of these, 67 % received solely palliative care. In the multivariate logistic models, the absence of the factor "necessity for mechanical ventilation on admission" (odds ratio 0.61; 95 % confidence interval (CI): 0.42 … 0.89) increased the chance for good outcome and the presence of this factor the risk of dying with an odds ratio of 8.07 (95 % CI: 4.54-14.34).

DISCUSSION

In spite of the severity of neurological deficits, significant functional progress has been made. These results could be interpret as positive proof of the efficacy of neurological/neurosurgical early rehabilitation programs.

摘要

背景

在德国,神经科 - 神经外科早期康复在严重神经疾病的治疗中已得到广泛应用。要制定质量标准,需要了解当前的康复进程。

患者与方法

对来自德国10个州16个中心的早期神经科/神经外科康复项目患者的康复进程进行回顾性分析。使用多变量逻辑回归模型研究预后良好或不良的几率。

结果

754名患者纳入研究。患者的平均年龄为68±15岁。在接受研究的患者中,26%在开始神经康复时使用机械通气。平均住院时间为56±51天。机械通气撤机率为65%,气管插管拔除率为54%。Barthel指数平均提高17分,吞咽困难(从62%降至30%)和依赖步行(从99%降至82%)显著减少,38%的患者达到C阶段(康复的下一阶段),这些仍可视为康复成功的迹象。在住院期间,近10%的患者死亡。其中,67%仅接受姑息治疗。在多变量逻辑模型中,不存在“入院时需要机械通气”这一因素(优势比0.61;95%置信区间(CI):0.42…0.89)增加了预后良好的几率,而存在该因素则增加了死亡风险,优势比为8.07(95%CI:4.54 - 14.34)。

讨论

尽管神经功能缺损严重,但仍取得了显著的功能进展。这些结果可被视为神经科/神经外科早期康复项目疗效的积极证据。

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