丝状病毒的气溶胶传播
Aerosol Transmission of Filoviruses.
作者信息
Mekibib Berhanu, Ariën Kevin K
机构信息
Virology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, Antwerp B-2000, Belgium.
School of Veterinary Medicine, College of Natural and Computational Sciences, Hawassa University, P.O. Box 05, Hawassa, Ethiopia.
出版信息
Viruses. 2016 May 23;8(5):148. doi: 10.3390/v8050148.
Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products. Since it was first identified in 1976, in the Democratic Republic of Congo (formerly Zaire) and Sudan, the 2013-2015 western African Ebola virus disease (EVD) outbreak is the largest, both by number of cases and geographical extension, and deadliest, recorded so far in medical history. The source of ebolaviruses for human index case(s) in most outbreaks is presumptively associated with handling of bush meat or contact with fruit bats. Transmission among humans occurs easily when a person comes in contact with contaminated body fluids of patients, but our understanding of other transmission routes is still fragmentary. This review deals with the controversial issue of aerosol transmission of filoviruses.
由于丝状病毒有可能通过国际旅行以及感染动物或动物产品的国际运输传入非流行国家，因此已成为全球公共卫生关注的问题。自1976年在刚果民主共和国（前扎伊尔）和苏丹首次发现以来，2013 - 2015年西非埃博拉病毒病（EVD）疫情是有记录以来在医学史上规模最大（就病例数量和地理范围而言）且最致命的疫情。在大多数疫情中，人类首例病例感染埃博拉病毒的源头据推测与接触丛林肉或与果蝠接触有关。当人接触到患者受污染的体液时，病毒很容易在人与人之间传播，但我们对其他传播途径的了解仍然不完整。本综述探讨了丝状病毒气溶胶传播这一有争议的问题。
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