Naderi Mahabadi Ali, Alhaddad Bassam, Ballou Stanley
Department of Medicine, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.
Departments of Medicine and Rheumatology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.
Case Rep Rheumatol. 2016;2016:4147068. doi: 10.1155/2016/4147068. Epub 2016 Jun 28.
Cardiac involvement is fairly common in patients with systemic lupus erythematosus (SLE). It may involve all layers of the heart and coronary arteries as well as the heart valves. We report an extremely rare presentation of valvulitis and valvular dysfunction associated with systemic lupus erythematosus. This is the first case of lupus valvulitis which required three mechanical prosthetic valve replacements with disease recurrence leading to a fatal outcome. This is, in our point of view, the consequence of aggressive natural history of the disease and perhaps late diagnosis and treatment of underlying SLE which was unsuccessful.
心脏受累在系统性红斑狼疮（SLE）患者中相当常见。它可能累及心脏的所有层、冠状动脉以及心脏瓣膜。我们报告了一例与系统性红斑狼疮相关的极其罕见的瓣膜炎和瓣膜功能障碍病例。这是第一例狼疮性瓣膜炎病例，该病例需要进行三次机械人工瓣膜置换，但疾病复发导致了致命结局。在我们看来，这是该疾病侵袭性自然病程的结果，也可能是潜在系统性红斑狼疮诊断和治疗延迟且未成功的结果。
