Wei Jie, Zeng Chao, Li Xiao-Xiao, Gong Qian-Yi, Lei Guang-Hua, Yang Tu-Bao
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan Province, 410008, China.
Health Management Center, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China.
J Health Popul Nutr. 2016 Oct 18;35(1):33. doi: 10.1186/s41043-016-0071-z.
A number of studies have reported the association between magnesium (Mg) and diabetes. However, the various conclusions were inconsistent and the data on the Chinese population was limited. The objective of this study was to evaluate the association among dietary Mg, serum Mg, and diabetes in Chinese adults.
A cross-sectional study that contained 2904 subjects was conducted. Biochemical test results and dietary intakes of subjects were collected for analysis. The adjusted odds ratios (ORs) and the corresponding 95 % confidence intervals (95 % CIs) were used to determine the relationship between Mg status and diabetes by logistic regression.
The prevalence of diabetes of the investigated population was 10.1 %. Dietary Mg intake was not significantly correlated with diabetes (P > 0.05). The significant negative association between serum Mg and diabetes existed, and the multivariate adjusted OR was 0.34 (95 % CI 0.24, 0.49) in model 3 for the highest quartile of serum Mg compared with the lowest. The P values for trend were all less than 0.001 for the relationship between serum Mg and diabetes. Dietary Mg intake and serum Mg were not significantly correlated in the diabetes population (P = 0.936).
Dietary Mg was not significantly correlated with diabetes, while serum Mg was inversely correlated with diabetes in the Chinese population. Meanwhile, dietary Mg intake and serum Mg were not significantly correlated in the diabetes population.
多项研究报告了镁（Mg）与糖尿病之间的关联。然而，各种结论并不一致，且关于中国人群的数据有限。本研究的目的是评估中国成年人饮食中的镁、血清镁与糖尿病之间的关联。
进行了一项包含2904名受试者的横断面研究。收集受试者的生化检测结果和饮食摄入量进行分析。采用调整后的比值比（OR）和相应的95%置信区间（95%CI），通过逻辑回归确定镁状态与糖尿病之间的关系。
被调查人群的糖尿病患病率为10.1%。饮食中镁的摄入量与糖尿病无显著相关性（P>0.05）。血清镁与糖尿病之间存在显著的负相关，在模型3中，血清镁最高四分位数与最低四分位数相比，多变量调整后的OR为0.34（95%CI 0.24，0.49）。血清镁与糖尿病之间关系的趋势P值均小于0.001。在糖尿病患者人群中，饮食中镁的摄入量与血清镁无显著相关性（P=0.936）。
在中国人群中，饮食中的镁与糖尿病无显著相关性，而血清镁与糖尿病呈负相关。同时，在糖尿病患者人群中，饮食中镁的摄入量与血清镁无显著相关性。
