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Seroprevalence and risk factors of Toxoplasma gondii infection among healthy blood donors in south-east of Iran.伊朗东南部健康献血者中弓形虫感染的血清流行率及危险因素
Parasite Immunol. 2015 Jul;37(7):362-7. doi: 10.1111/pim.12198.
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Prevalence of immunity to toxoplasmosis among Iranian childbearing age women: Systematic review and meta-analysis.伊朗育龄妇女弓形虫病免疫流行率:系统评价与荟萃分析。
Iran J Reprod Med. 2013 Nov;11(11):861-8.
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Congenital toxoplasmosis.先天性弓形虫病
BMJ Clin Evid. 2013 Aug 29;2013:0906.
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Epidemiology of and diagnostic strategies for toxoplasmosis.弓形虫病的流行病学和诊断策略。
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Serologic evaluation of toxoplasmosis in matrimonial women in Babol, Iran.伊朗巴博勒已婚女性弓形虫病的血清学评估
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Prevention of toxoplasmosis in transplant patients.移植患者弓形虫病的预防
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Seroepidemiology of infection with Toxoplasma gondii in healthy blood donors of Durango, Mexico.墨西哥杜兰戈健康献血者弓形虫感染的血清流行病学研究。
BMC Infect Dis. 2007 Jul 13;7:75. doi: 10.1186/1471-2334-7-75.
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Fatal disseminated toxoplasmosis during primary HIV infection.原发性HIV感染期间的致命性播散性弓形虫病。
Curr HIV Res. 2007 Mar;5(2):273-4. doi: 10.2174/157016207780077011.
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Toxoplasmosis: beyond animals to humans.弓形虫病:从动物到人类
Trends Parasitol. 2006 Mar;22(3):137-42. doi: 10.1016/j.pt.2006.01.007. Epub 2006 Jan 30.
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Toxoplasma gondii: transmission, diagnosis and prevention.刚地弓形虫:传播、诊断与预防
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伊朗东南部克尔曼市育龄妇女中的感染血清阳性率。

Seroprevalence of infection among childbearing age women in Kerman city, southeastern Iran.

作者信息

Tavakoli Kareshk Amir, Keyhani Amir, Asadi Arash, Zia-Ali Naser, Mahmoudvand Hossein, Mohammadi Ali Reza

机构信息

Department of Medical Parasitology and Mycology, Kerman University of Medical Sciences, Kerman, Iran.

Health and Treatment Center of Komijan, Arak University of Medical Sciences, Arak, Iran.

出版信息

J Parasit Dis. 2016 Dec;40(4):1544-1547. doi: 10.1007/s12639-015-0724-7. Epub 2015 Oct 7.

DOI:10.1007/s12639-015-0724-7
PMID:27876979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5118350/
Abstract

This cross-sectional study aims to determine the prevalence of IgM and IgG anti-. antibodies and the associated risk factors among childbearing age women referring to counseling centers before marriage in Kerman city, southeast of Iran. Totally, 300 serum samples were collected from women referred to Central Laboratory for Marriage Consultation in Kerman city were screened for IgG and IgM anti- antibodies by enzyme linked immunosorbent assay (ELISA). Out of the 300 serum samples, 38 (12.6 %) tested seropositive for anti- antibodies; 31 (10.3 %) samples tested seropositive for only IgG antibody, 1 (0.33 %) tested seropositive for both IgM and IgG and 6 (2.0 %) were positive for IgM antibody alone. Statistical analyses also indicated that seroprevalence of anti- antibodies increased with age ( < 0.05). Moreover, some risk factors such as, living in rural regions, contact with cats, raw/half-cooked meat consumption, and agricultural activities were significantly ( < 0.05) related to seropositivity. The findings revealed that more than three-quarters of the childbearing age women studied in the present investigation are susceptible to infection during pregnancy. Thus, by adopting correct and improved practices we can improve their living conditions, and prevent infection and awareness and control of pathogens associated with disease is recommended.

摘要

这项横断面研究旨在确定伊朗东南部克尔曼市婚前前往咨询中心的育龄妇女中抗……抗体IgM和IgG的流行率及其相关危险因素。总共从前往克尔曼市婚姻咨询中央实验室的妇女中收集了300份血清样本,采用酶联免疫吸附测定法(ELISA)检测抗……抗体的IgG和IgM。在这300份血清样本中,38份(12.6%)抗……抗体检测呈血清阳性;31份(10.3%)样本仅IgG抗体检测呈血清阳性,1份(0.33%)IgM和IgG均检测呈血清阳性,6份(2.0%)仅IgM抗体呈阳性。统计分析还表明,抗……抗体的血清流行率随年龄增长而增加(P<0.05)。此外,一些危险因素,如生活在农村地区、接触猫、食用生肉/半熟肉以及从事农业活动,与血清阳性显著相关(P<0.05)。研究结果显示,本调查中超过四分之三的育龄妇女在怀孕期间易受感染。因此,通过采取正确和改进的做法,我们可以改善她们的生活条件,并预防感染,建议提高对与疾病相关病原体的认识并加以控制。