Xu Min, Xu Guiping, Yang Yang
Neuroimaging Laboratory, School of Biomedical Engineering, Shenzhen University Health Science CenterShenzhen, China; Center for Neuroimaging, Shenzhen Institute of NeuroscienceShenzhen, China; Guangdong Key Laboratory of Biomedical Information Detection and Ultrasound Imaging, Shenzhen UniversityShenzhen, China.
Department of Psychology, Guangdong University of Education Guangzhou, China.
Front Behav Neurosci. 2016 Nov 15;10:220. doi: 10.3389/fnbeh.2016.00220. eCollection 2016.
Understanding how the nature of interference might influence the recruitments of the neural systems is considered as the key to understanding cognitive control. Although, interference processing in the emotional domain has recently attracted great interest, the question of whether there are separable neural patterns for emotional and non-emotional interference processing remains open. Here, we performed an activation likelihood estimation meta-analysis of 78 neuroimaging experiments, and examined common and distinct neural systems for emotional and non-emotional interference processing. We examined brain activation in three domains of interference processing: emotional verbal interference in the face-word conflict task, non-emotional verbal interference in the color-word Stroop task, and non-emotional spatial interference in the Simon, SRC and Flanker tasks. Our results show that the dorsal anterior cingulate cortex (ACC) was recruited for both emotional and non-emotional interference. In addition, the right anterior insula, presupplementary motor area (pre-SMA), and right inferior frontal gyrus (IFG) were activated by interference processing across both emotional and non-emotional domains. In light of these results, we propose that the anterior insular cortex may serve to integrate information from different dimensions and work together with the dorsal ACC to detect and monitor conflicts, whereas pre-SMA and right IFG may be recruited to inhibit inappropriate responses. In contrast, the dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC) showed different degrees of activation and distinct lateralization patterns for different processing domains, which suggests that these regions may implement cognitive control based on the specific task requirements.
理解干扰的本质如何影响神经系统的招募被认为是理解认知控制的关键。尽管情感领域的干扰处理最近引起了极大的兴趣，但情感和非情感干扰处理是否存在可分离的神经模式这一问题仍未解决。在此，我们对78项神经影像学实验进行了激活可能性估计元分析，并研究了情感和非情感干扰处理的共同和不同的神经系统。我们在干扰处理的三个领域检查了大脑激活情况：面孔-单词冲突任务中的情感言语干扰、颜色-单词Stroop任务中的非情感言语干扰以及Simon、SRC和Flanker任务中的非情感空间干扰。我们的结果表明，背侧前扣带回皮质（ACC）在情感和非情感干扰中均被激活。此外，右侧前岛叶、补充运动前区（pre-SMA）和右侧额下回（IFG）在情感和非情感领域的干扰处理中均被激活。鉴于这些结果，我们提出前岛叶皮质可能用于整合来自不同维度的信息，并与背侧ACC协同工作以检测和监测冲突，而pre-SMA和右侧IFG可能被招募来抑制不适当的反应。相比之下，背外侧前额叶皮质（DLPFC）和顶叶后皮质（PPC）在不同的处理领域表现出不同程度的激活和明显的偏侧化模式，这表明这些区域可能根据特定的任务要求实施认知控制。
