Sharma Y K, Bansal Prakhar, Menon Shruti, Prakash Naren
Department of Dermatology, Dr. D. Y. Patil Medical College, Pune, India.
Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S77-S80. doi: 10.1016/j.dsx.2016.12.009. Epub 2016 Dec 15.
To assess the prevalence of metabolic syndrome and its correlation with the severity and duration of vitiligo.
One hundred vitiligo patients and 100 age-and-sex matched controls were included, whose waist circumference and blood pressure were measured; fasting serum cholesterol, triglycerides and glucose levels quantified; disease severity assessed and metabolic syndrome defined by National Cholesterol Education Program (NCEP) criteria.
Metabolic syndrome (24%:12%), hypertriglyceridemia (41%:24%), impaired glucose tolerance (25%:16%) [P<0.05] and low HDL (P=0.044) were significantly more prevalent in cases as compared to controls as were the mean values of triglycerides and fasting blood sugar. Increased mean age of vitiligo patients correlated with the presence of metabolic syndrome.
Metabolic syndrome had significant presence in but remained unaffected by the severity of vitiligo in our study patients.
评估代谢综合征的患病率及其与白癜风严重程度和病程的相关性。
纳入100例白癜风患者和100例年龄及性别匹配的对照者，测量其腰围和血压；定量测定空腹血清胆固醇、甘油三酯和血糖水平；评估疾病严重程度，并根据美国国家胆固醇教育计划（NCEP）标准定义代谢综合征。
与对照组相比，病例组中代谢综合征（24%:12%）、高甘油三酯血症（41%:24%）、糖耐量受损（25%:16%）[P<0.05]和低高密度脂蛋白（P=0.044）的患病率显著更高，甘油三酯和空腹血糖的平均值也是如此。白癜风患者的平均年龄增加与代谢综合征的存在相关。
在我们的研究患者中，代谢综合征显著存在，但不受白癜风严重程度的影响。
