Saric Suzana, Notay Manisha, Sivamani Raja K
School of Medicine, University of California-Davis, Sacramento, CA 95817, USA.
Department of Dermatology, University of California-Davis, Sacramento, CA 95816, USA.
Antioxidants (Basel). 2016 Dec 29;6(1):2. doi: 10.3390/antiox6010002.
Polyphenols are antioxidant molecules found in many foods including nuts, fruits, vegetables, chocolate, wine, and tea. Polyphenols have antimicrobial, anti-inflammatory, and antineoplastic properties. Recent studies suggest that tea polyphenols may be used for reducing sebum production in the skin and for treatment of acne vulgaris. This review examines the evidence for use of topically and orally ingested tea polyphenols against sebum production and for acne treatment and prevention. The PubMed database was searched for studies on tea polyphenols, sebum secretion, and acne vulgaris. Of the 59 studies found, eight met the inclusion criteria. Two studies evaluated tea polyphenol effects on sebum production; six studies examined tea polyphenol effects on acne vulgaris. Seven studies evaluated topical tea polyphenols; one study examined systemic tea polyphenols. None of the studies evaluated both topical and systemic tea polyphenols. Tea polyphenol sources included green tea (six studies) and tea, type not specified (two studies). Overall, there is some evidence that tea polyphenols in topical formulation may be beneficial in reducing sebum secretion and in treatment of acne. Research studies of high quality and with large sample sizes are needed to assess the efficacy of tea polyphenols in topical and oral prevention of acne vulgaris and lipid synthesis by the sebaceous glands.
多酚是存在于许多食物中的抗氧化分子，这些食物包括坚果、水果、蔬菜、巧克力、葡萄酒和茶。多酚具有抗菌、抗炎和抗肿瘤特性。最近的研究表明，茶多酚可用于减少皮肤皮脂分泌以及治疗寻常痤疮。这篇综述探讨了局部应用和口服茶多酚针对皮脂分泌以及痤疮治疗与预防方面的证据。检索了PubMed数据库中关于茶多酚、皮脂分泌和寻常痤疮的研究。在找到的59项研究中，有8项符合纳入标准。两项研究评估了茶多酚对皮脂分泌的影响；六项研究考察了茶多酚对寻常痤疮的影响。七项研究评估了局部应用的茶多酚；一项研究考察了全身性的茶多酚。没有研究同时评估局部和全身性的茶多酚。茶多酚来源包括绿茶（六项研究）和未指明类型的茶（两项研究）。总体而言，有一些证据表明局部制剂中的茶多酚可能有助于减少皮脂分泌和治疗痤疮。需要高质量且大样本量的研究来评估茶多酚在局部和口服预防寻常痤疮以及皮脂腺脂质合成方面的功效。
