Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Bosn J Basic Med Sci. 2010 Aug;10(3):260-4. doi: 10.17305/bjbms.2010.2697.
This study was aimed to depict potential effects of stable formulation (water in oil emulsion), containing 3% green tea (Camellia sinensis L) extract on skin sebum production in healthy human volunteers. For this purpose formulation was designed using 3% ethanolic green tea extract and Abil®EM90 was used as an emulsifier. Formulation was applied to the cheeks of healthy human volunteers (n=10) for a period of 8 weeks. Measurements for skin sebum production were considered using Sebumeter MPA 5. Results were compiled and any effect produced by the formulation was justified statistically. It was observable that statistically significant (p < 0.5%) results were found for skin sebum production after long term application of the formulation. 3% formulation of green tea extract was ideal in all aspects and can be experienced in skin disorders like acne to further investigate its effects in unhealthy volunteers.
本研究旨在描述含有 3%绿茶(Camellia sinensis L)提取物的稳定制剂(油包水乳液)对健康人体皮脂分泌的潜在影响。为此,我们使用 3%乙醇绿茶提取物设计了配方,并使用 Abil®EM90 作为乳化剂。将配方应用于健康人体志愿者的脸颊上,为期 8 周。使用 Sebumeter MPA 5 测量皮脂分泌量。编译结果并通过统计学方法证明配方的任何作用。结果表明,经过长期应用该配方后,皮脂分泌量有统计学意义(p < 0.5%)。3%的绿茶提取物配方在各方面都是理想的,可以在痤疮等皮肤疾病中体验到,以进一步研究其在非健康志愿者中的效果。