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伊朗铜T-380A宫内节育器与继发性不孕之间不存在关联。

Lack of Association between Cu T-380A Intrauterine Device and Secondary Infertility in Iran.

作者信息

Abdinasab Mahnaz, Dehghani Firouzabadi Razieh, Farajkhoda Tahmineh, Abdoli Ali Mohammad

机构信息

Yazd Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Research Center for Nursing and Midwifery Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Int J Fertil Steril. 2017 Jan-Mar;10(4):343-349. doi: 10.22074/ijfs.2016.5085. Epub 2016 Nov 1.

Abstract

BACKGROUND

The appropriate choice of a contraceptive method has been a major issue in reproductive health research. Cu T intrauterine device (Cu T IUD) has been introduced as one of the most effective contraceptive methods in the world, however, the relationship between prior use of Cu T IUD and secondary infertility has not been evaluated in Iran. To examine the association of Cu T-380A IUD and secondary infertility in Iran.

MATERIALS AND METHODS

A retrospective cohort study was conducted from December 2010 to September 2011 in the Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. A total of 750 married women (15-49 years old) with at least one parity, whom were referred to four educational healthcare centers of Shahid Sadoughi University of Medical Sciences, were selected as participants. They were divided into two groups (case and control) based on previous history of using Cu T-380A IUD. Data were gathered using a standard reliable questionnaire along with a face-to-face interview and were analyzed with descriptive and analytical (χ²) tests.

RESULTS

Mean period of Cu T-380A IUD usage in the case group was 57.46 ± 47.74 months and mean time length from Cu T-380A IUD removal to pregnancy was 14.87 ± 5.18 months in this group. We observed no relationship between the use of Cu T-380A IUD and frequency of secondary infertility (3.5% in the case group versus 2.7% in the control group, P=0.52).

CONCLUSION

Given the relatively large sample size studied here, it is unlikely that Cu T-380A IUD results in secondary infertility and may be used by Iranian women as a safe contraceptive method.

摘要

背景

避孕方法的恰当选择一直是生殖健康研究中的一个主要问题。铜T宫内节育器(Cu T IUD)已被列为世界上最有效的避孕方法之一,然而,伊朗尚未评估过先前使用铜T IUD与继发性不孕之间的关系。旨在研究伊朗铜T - 380A宫内节育器与继发性不孕之间的关联。

材料与方法

2010年12月至2011年9月,在伊朗亚兹德沙希德萨杜基医科大学不孕不育研究与临床中心进行了一项回顾性队列研究。总共750名已婚女性(年龄在15 - 49岁之间,至少生育过一次)被选为研究对象,她们被转介到沙希德萨杜基医科大学的四个教育医疗中心。根据先前使用铜T - 380A宫内节育器的病史,她们被分为两组(病例组和对照组)。通过标准可靠的问卷以及面对面访谈收集数据,并采用描述性和分析性(χ²)检验进行分析。

结果

病例组中铜T - 380A宫内节育器的平均使用时间为57.46 ± 47.74个月,该组从取出铜T - 380A宫内节育器到怀孕的平均时间为14.87 ± 5.18个月。我们观察到使用铜T - 380A宫内节育器与继发性不孕的发生率之间没有关系(病例组为3.5%,对照组为2.7%,P = 0.52)。

结论

鉴于本研究的样本量相对较大,铜T - 380A宫内节育器导致继发性不孕的可能性不大,伊朗女性可以将其作为一种安全的避孕方法使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d55/5134749/7fe5f41b215e/Int-J-Fertil-Steril-10-343-g01.jpg

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