Ma Jie, Li Chuang-Jun, Yang Jing-Zhi, Sun Hua, Zhang Dong-Ming
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Molecules. 2017 Jan 18;22(1):133. doi: 10.3390/molecules22010133.
A new phenylpropanoid glycoside (), and two new coumarin glycosides (, ), together with two known compounds (, ), have been isolated from the stems of Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound (50 μM) exhibited significant hepatoprotective activity against -acetyl-p-aminophenol (APAP)-induced HepG2 cell damage assays.
从狭叶珍珠菜的茎中分离出一种新的苯丙素苷（）、两种新的香豆素苷（，）以及两种已知化合物（，）。通过光谱和化学方法确定了它们的结构。此外，在对乙酰氨基酚（APAP）诱导的HepG2细胞损伤试验中，化合物（50 μM）表现出显著的肝保护活性。
