Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 "Neuroimaging &Psychiatry", University Paris Sud - University Paris Saclay, University Paris Descartes, 97 Bd de Port Royal, 75014, Paris, France.
National Institute for Health and Welfare, Department of Health, Unit of Mental Health, P.O. Box 30, 00271 Helsinki, Finland.
Sci Rep. 2017 Feb 9;7:41678. doi: 10.1038/srep41678.
Here we report the first and most robust evidence about how sleep habits are associated with regional brain grey matter volumes and school grade average in early adolescence. Shorter time in bed during weekdays, and later weekend sleeping hours correlate with smaller brain grey matter volumes in frontal, anterior cingulate, and precuneus cortex regions. Poor school grade average associates with later weekend bedtime and smaller grey matter volumes in medial brain regions. The medial prefrontal - anterior cingulate cortex appears most tightly related to the adolescents' variations in sleep habits, as its volume correlates inversely with both weekend bedtime and wake up time, and also with poor school performance. These findings suggest that sleep habits, notably during the weekends, have an alarming link with both the structure of the adolescent brain and school performance, and thus highlight the need for informed interventions.
在这里，我们首次报告了最有力的证据，证明睡眠习惯与青少年早期的区域脑灰质体积和学校年级平均成绩有关。工作日睡眠时间较短，周末睡眠时间较晚与额前皮质、前扣带和楔前叶皮质区域的脑灰质体积较小有关。较差的学校平均成绩与周末较晚的就寝时间和内侧脑区较小的灰质体积有关。内侧前额叶-前扣带皮层与青少年睡眠习惯的变化关系最为密切，因为其体积与周末的就寝时间和起床时间以及较差的学业成绩呈负相关。这些发现表明，睡眠习惯，特别是在周末，与青少年大脑结构和学业成绩之间存在惊人的联系，因此强调了需要进行明智的干预。
