Kaur Gunpreet, Gupta Vikas, Bansal Parveen
Department of Herbal Drug Technology, University Centre of Excellence in Research, Baba Farid University of Health Sciences, Faridkot, Punjab, India.
J Adv Pharm Technol Res. 2017 Jan-Mar;8(1):39-42. doi: 10.4103/2231-4040.197393.
Herbal medicine is the oldest form of healthcare known to humanity. Recently, much attention is being directed toward the use of antioxidants. There are some very commonly used Ayurvedic preparations that might have inbuilt antioxidant activity, and their therapeutic potential can be partially attributable to its antioxidant activity. Hence, it was proposed to find out antioxidant activity of such common formulations. Estimation of innate antioxidant activity of some commonly used traditional formulations. In this study, five formulations were evaluated for antioxidant activity in comparison to gallic acid (standard) using the reducing power method and superoxide radical scavenging activity by dimethyl sulfoxide method followed by calculation of scavenging activity and inhibitory concentration 50% (IC). The result shows that Ayurvedic drug extracts possess good reducing power and antioxidant activity. shows higher reducing power ranging from 117 ± 0.021 to 0.176 ± 0.012 as compared to other extracts. The drug extracts were also found to be an efficient scavenger of superoxide radical. The IC values for , , , , gallic acid (standard) and , were found to be 50.07, 98.41, 105.13, 116.39, 176.80, and 200.17, respectively. From this study, it can be concluded that the above Ayurvedic formulations possess antioxidant property. However, work could be initiated on the isolation and identification of these antioxidant components.
草药是人类已知的最古老的医疗保健形式。最近，人们对抗氧化剂的使用给予了很多关注。有一些非常常用的阿育吠陀制剂可能具有内在的抗氧化活性，其治疗潜力可能部分归因于其抗氧化活性。因此，有人提议研究此类常见制剂的抗氧化活性。评估一些常用传统制剂的固有抗氧化活性。在本研究中，使用还原力法和二甲基亚砜法测定超氧自由基清除活性，并计算清除活性和半数抑制浓度（IC），将五种制剂与没食子酸（标准品）进行抗氧化活性比较。结果表明，阿育吠陀药物提取物具有良好的还原力和抗氧化活性。与其他提取物相比，其还原力更高，范围从117±0.021至0.176±0.012。还发现药物提取物是超氧自由基的有效清除剂。 、 、 、 、没食子酸（标准品）和 的IC值分别为50.07、98.41、105.13、116.39、176.80和200.17。从这项研究可以得出结论，上述阿育吠陀制剂具有抗氧化特性。然而，可以着手对这些抗氧化成分进行分离和鉴定。
