Adibi Peyman, Keshteli Ammar Hasanzadeh, Daghaghzadeh Hamed, Roohafza Hamidreza, Pournaghshband Nasim, Afshar Hamid
Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2016 Dec 27;5:195. doi: 10.4103/2277-9175.190936. eCollection 2016.
Current studies have indicated a high ratio of psychological problems in functional dyspepsia (FD) which causes disturbance in its management, so recognition these problems help the process of treatment.
This was a cross-sectional study with a sample size of 4763 carried out in Isfahan University of Medical Sciences in 2011. Modified ROME III questionnaire was used to evaluate FD symptoms. Hospital anxiety and depression scale and 12-item General Health Questionnaire-12 was used to assess the psychological issue. Logistic regression analysis was used to assess the association of psychological problems and FD.
We showed that overly 654 (13.7%), 1338 (28.1%), and 1067 (22.4%) of participants, respectively had anxiety, depression, and of psychological distress. Seven hundred and ten (15.5%) participants were diagnosed with FD. Of all participants Mean scores of anxiety ( < 0.001), depression ( < 0.001), and psychological distress ( < 0.001) in participants with FD were significantly more than those with no FD. Multivariate logistic regression analysis showed that psychological problems, whether in the form of psychological distress odds ratio (OR): 2 (95% confidence interval [CI]: 1.3-3) and OR: 1.3 (95% CI: 1.1-1.7) in males and females, respectively, anxiety OR: 2.4 (95% CI: 1.5-3.9) and OR: 2.3 (95% CI: 1.7-3.2) in males and females, respectively) or depression OR: 2.2 (95% CI: 1.5-3.3) and OR: 1.7 (95% CI: 1.3-2.3) in males and females, respectively) were significantly linked to FD in both genders.
The prevalence of FD is less in males than females, but psychological links were stronger in males. Thus, it is essential to consider and detect the psychological distress in these patients.
目前的研究表明，功能性消化不良（FD）患者中存在心理问题的比例较高，这给其治疗带来困扰，因此识别这些问题有助于治疗进程。
这是一项横断面研究，2011年在伊斯法罕医科大学开展，样本量为4763。采用改良的罗马III问卷评估FD症状。使用医院焦虑抑郁量表和12项一般健康问卷-12评估心理问题。采用逻辑回归分析评估心理问题与FD的关联。
我们发现，分别有超过654名（13.7%）、1338名（28.1%）和1067名（22.4%）参与者存在焦虑、抑郁和心理困扰。710名（15.5%）参与者被诊断为FD。在所有参与者中，FD患者的焦虑（<0.001）、抑郁（<0.001）和心理困扰（<0.001）平均得分显著高于无FD者。多变量逻辑回归分析显示，心理问题，无论是以心理困扰的形式（男性的比值比[OR]：2[95%置信区间（CI）：1.3 - 3]，女性的OR：1.3[95%CI：1.1 - 1.7]）、焦虑的形式（男性的OR：2.4[95%CI：1.5 - 3.9]，女性的OR：2.3[95%CI：1.7 - 3.2]）还是抑郁的形式（男性的OR：2.2[95%CI：1.5 - 3.3]，女性的OR：1.7[95%CI：1.3 - 2.3]），在两性中均与FD显著相关。
FD的患病率男性低于女性，但心理关联在男性中更强。因此，在这些患者中考虑并检测心理困扰至关重要。
