Gevers Dirk, Kugathasan Subra, Knights Dan, Kostic Aleksandar D, Knight Rob, Xavier Ramnik J
Janssen Human Microbiome Institute at Janssen Research and Development LLC, Cambridge, MA 02142, USA.
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University, Atlanta, GA 30322, USA.
Cell Host Microbe. 2017 Mar 8;21(3):301-304. doi: 10.1016/j.chom.2017.02.012.
Our 2014 study published in Cell Host & Microbe, "The Treatment-Naive Microbiome in New-Onset Crohn's Disease," was designed to improve our understanding of the microbiome's role in Crohn's disease by studying a unique, well-suited cohort and sample set. This commentary provides a hindsight perspective of this original study as well as future outlook.
我们于2014年发表在《细胞宿主与微生物》杂志上的研究“初发性克罗恩病中未经治疗的微生物组”,旨在通过研究一个独特且非常合适的队列和样本集,增进我们对微生物组在克罗恩病中作用的理解。本评论提供了对这项原始研究的事后回顾视角以及未来展望。