University of British Columbia, 2136 West Mall, Vancouver, BC, V6T 1Z4, Canada.
Stanford University, Bldg. 420, Jordan Hall, Stanford, CA, 94305, USA.
J Abnorm Child Psychol. 2018 Jan;46(1):159-167. doi: 10.1007/s10802-017-0285-6.
Depressed adolescents are characterized by negative interpretation biases. Although investigators have used cognitive bias modification for interpretation (CBM-I) to experimentally manipulate interpretation biases in depressed adults, the near- and far-transfer effects are not well understood in adolescents diagnosed with Major Depressive Disorder (MDD). In this study, we extend previous research by investigating the near- and far-transfer effects of 6 sessions of Positive versus Neutral CBM-I on independent measures of interpretation bias (near-transfer effects) and on attention biases and clinical symptoms (far-transfer effects) in a sample of adolescents with MDD (n = 46). At post-training, adolescents who received Positive CBM-I interpreted ambiguous scenarios more positively than did participants who received Neutral CBM-I, providing evidence of training effectiveness. There was no evidence, however, of near- or far-transfer effects. These findings raise concerns about the malleability of interpretation biases in adolescent depression and suggest that further work is needed to establish the clinical utility of CBM-I for adolescents with MDD.
抑郁青少年的特点是存在消极的解释偏差。虽然研究人员已经使用认知偏差修正（CBM-I）来对抑郁成年人群体的解释偏差进行实验性操纵，但在被诊断为重度抑郁症（MDD）的青少年中，其近转移和远转移效应尚不清楚。在这项研究中，我们通过调查 6 次积极与中性 CBM-I 的近转移和远转移效应对 MDD 青少年（n=46）的解释偏差（近转移效应）和注意偏差以及临床症状（远转移效应）的独立测量，扩展了先前的研究。在训练后，接受积极 CBM-I 的青少年对模棱两可的场景的解释比接受中性 CBM-I 的参与者更积极，这提供了训练效果的证据。然而，没有近转移或远转移效应的证据。这些发现引起了人们对青少年抑郁症中解释偏差的可塑性质的关注，并表明需要进一步研究来确定 CBM-I 对 MDD 青少年的临床实用性。
