Mental Health and Addiction Research Group, Department of Health Sciences, University of York, UK.
School of Psychology, Deakin University, Burwood, Victoria, Australia.
Psychol Psychother. 2017 Dec;90(4):770-796. doi: 10.1111/papt.12121. Epub 2017 Mar 16.
Depression is currently the leading cause of illness and disability in young people. Evidence suggests that behavioural activation (BA) is an effective treatment for depression in adults but less research focuses on its application with young people. This review therefore examined whether BA is effective in the treatment of depression in young people.
A systematic review (International Prospective Register of Systematic Reviews reference: CRD42015020453), following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, was conducted to examine studies that had explored behavioural interventions for young people with depression. The electronic databases searched included the Cochrane Library, EMBASE, MEDLINE, CINAHL Plus, PsychINFO, and Scopus. A meta-analysis employing a generic inverse variance, random-effects model was conducted on the included randomized controlled trials (RCTs) to examine whether there were overall effects of BA on the Children's Depression Rating Scale - Revised.
Ten studies met inclusion criteria: three RCTs and seven within-participant designs (total n = 170). The review showed that BA may be effective in the treatment of depression in young people. The Cochrane risk of bias tool and the Moncrieff scale used to assess the quality of the included studies revealed a variety of limitations within each.
Despite demonstrating that BA may be effective in the treatment of depression in young people, the review indicated a number of methodological problems in the included studies meaning that the results and conclusions should be treated with caution. Furthermore, the paucity of studies in this area highlights the need for further research.
Currently BA is included within National Institute for Health and Clinical Excellence (NICE, 2009) guidelines as an evidence-based treatment for depression in adults with extensive research supporting its effectiveness. It is important to investigate whether it may also be effective in treating young people. Included studies reported reductions in depression scores across a range of measures following BA. BA may be an effective treatment of depression in young people.
目前,抑郁症是导致年轻人患病和残疾的主要原因。有证据表明,行为激活(BA)是一种有效的成人抑郁症治疗方法,但针对年轻人的应用研究较少。因此,本综述旨在考察 BA 是否对年轻人的抑郁症治疗有效。
本研究采用系统综述(国际前瞻性注册系统综述参考号:CRD42015020453),遵循系统综述和荟萃分析报告的首选项目,对探讨针对患有抑郁症的年轻人的行为干预措施的研究进行了考察。检索的电子数据库包括 Cochrane 图书馆、EMBASE、MEDLINE、CINAHL Plus、PsychINFO 和 Scopus。对纳入的随机对照试验(RCT)进行了通用逆方差、随机效应模型的荟萃分析,以考察 BA 是否对儿童抑郁评定量表修订版有总体影响。
符合纳入标准的研究有 10 项:三项 RCT 和七项自身对照设计(共纳入 170 名参与者)。综述表明,BA 可能对年轻人的抑郁症治疗有效。Cochrane 风险偏倚工具和 Moncrieff 量表用于评估纳入研究的质量,结果显示每个研究都存在各种局限性。
尽管 BA 可能对年轻人的抑郁症治疗有效,但综述表明纳入研究存在若干方法学问题,因此应谨慎对待结果和结论。此外,该领域研究的缺乏凸显了进一步研究的必要性。
目前,BA 已被纳入国家卫生与临床优化研究所(NICE,2009 年)的指南,作为成人抑郁症的循证治疗方法,其有效性得到了广泛的研究支持。因此,有必要研究其是否也对年轻人有效。纳入的研究报告称,在接受 BA 治疗后,各种抑郁评分均有所降低。BA 可能是治疗年轻人抑郁症的有效方法。