聚酮合酶模块的重新定义。
Polyketide Synthase Modules Redefined.
机构信息
Department of Molecular Biosciences, The University of Texas at Austin, 100 E. 24th St., Austin, TX, 78712, USA.
出版信息
Angew Chem Int Ed Engl. 2017 Apr 18;56(17):4658-4660. doi: 10.1002/anie.201701281. Epub 2017 Mar 21.
Abstract
Modular redefinition: A long-standing paradigm in modular polyketide synthase enzymology, namely the definition of a module, has been challenged by Abe and co-workers in their recent study. With this new understanding has emerged renewed hope for engineering these assembly lines to produce new materials and medicines.
摘要
模块化重定义
模块聚酮合酶酶学中长期存在的一个范例，即模块的定义，最近受到 Abe 及其同事的研究挑战。随着这一新认识的出现，人们重新燃起了对这些装配线进行工程改造以生产新材料和药物的希望。
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