Oberjé Edwin J M, Tanke Marit A C, Jeurissen Patrick P T
Faculty of Healthcare, Zuyd University of Applied Sciences, Heerlen.
Radboud University Medical Center, Celsus Academy for Sustainable Healthcare, Nijmegen.
Infect Dis Rep. 2017 Mar 30;9(1):6800. doi: 10.4081/idr.2017.6800.
Antimicrobial stewardship is recognized as a key component to stop the current European spread of antimicrobial resistance. It has also become evident that antimicrobial resistance is a problem that cannot be tackled by single institutions or physicians. Prevention of antimicrobial resistance needs rigorous actions at ward level, institution level, national level and at supra-national levels. Countries can learn from each other and possibly transplant best practices across borders to prevent antimicrobial resistance. The aim of this study is to highlight some of the success stories of proven cost-effective interventions, and to describe the actions that have been taken, the outcomes that have been found, and the difficulties that have been met. In some cases we came across substantial scope for real-life cost savings. Although the best approach to effectively hinder the spread of antimicrobial resistance remains unclear and may vary significantly among settings, several EU-wide examples demonstrate that cost-effective antimicrobial stewardship is possible. Such examples can encourage others to implement (the most cost-effective) elements in their system.
抗菌药物管理被认为是阻止当前抗菌药物耐药性在欧洲蔓延的关键组成部分。同样明显的是，抗菌药物耐药性问题无法由单个机构或医生解决。预防抗菌药物耐药性需要在病房层面、机构层面、国家层面和超国家层面采取严格行动。各国可以相互学习，并有可能跨境移植最佳做法以预防抗菌药物耐药性。本研究的目的是突出一些已证实具有成本效益的干预措施的成功案例，并描述已采取的行动、已取得的成果以及遇到的困难。在某些情况下，我们发现了实际节省成本的巨大空间。尽管有效阻碍抗菌药物耐药性传播的最佳方法仍不明确，且在不同环境中可能有很大差异，但一些全欧盟范围的例子表明，具有成本效益的抗菌药物管理是可行的。这些例子可以鼓励其他国家在其系统中实施（最具成本效益的）要素。
