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希腊克里特岛农村地区痴呆症、抑郁症和轻度认知障碍的患病率

Prevalence of Dementia, Depression, and Mild Cognitive Impairment in a Rural Area of the Island of Crete, Greece.

作者信息

Tsolaki Magda, Gkioka Mara, Verykouki Eleni, Galoutzi Niki, Kavalou Eirini, Pattakou-Parasyri Vassiliki

机构信息

1 Department of Neurology, "G.H. Papanikolaou", School of Medicine, Aristotle University of Thessaloniki, Greece.

2 Greek Alzheimer Association and Related Disorders, Thessaloniki, Greece (GAARD).

出版信息

Am J Alzheimers Dis Other Demen. 2017 Aug;32(5):252-264. doi: 10.1177/1533317517698789. Epub 2017 May 4.

Abstract

The studies on the prevalence of dementia, depression, and mild cognitive impairment (MCI) in Greece are sparse and show major variations of prevalence depending on geographical areas, nutritional habits, and the way of living. The aim of this door-to-door study was to find the prevalence of dementia, depression, and MCI in a rural Greek population. Four hundred and forty-three individuals older than 61years following the application of specific criteria were diagnosed with: normal cognition, depression, MCI with and without depression, and dementia with and without depression. Four diagnostic methods were used, 2 of which included Mungas correction for age and education. After Mungas adjustment, the results were as follows-depression: 33.9%; MCI: 15.3%; MCI with depression: 8.6%; dementia: 2.0%; and dementia with depression: 7.2%. Dementia is less prevalent compared to global data and other Greek areas. Mild cognitive impairment is more prevalent than dementia. High percentages of depression may be related to low education.

摘要

关于希腊痴呆症、抑郁症和轻度认知障碍(MCI)患病率的研究较少,且显示患病率因地理区域、营养习惯和生活方式的不同而存在很大差异。这项挨家挨户进行的研究旨在查明希腊农村人口中痴呆症、抑郁症和MCI的患病率。在应用特定标准后,443名61岁以上的个体被诊断为:认知正常、抑郁症、伴或不伴抑郁症的MCI以及伴或不伴抑郁症的痴呆症。使用了四种诊断方法,其中两种包括对年龄和教育程度的蒙加斯校正。经过蒙加斯调整后,结果如下:抑郁症33.9%;MCI 15.3%;伴抑郁症的MCI 8.6%;痴呆症2.0%;伴抑郁症的痴呆症7.2%。与全球数据和希腊其他地区相比,痴呆症的患病率较低。轻度认知障碍比痴呆症更为普遍。高比例的抑郁症可能与低教育程度有关。

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