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Emergence of fluoroquinolone resistance in Bacteroides fragilis accompanied by resistance to beta-lactam antibiotics.脆弱拟杆菌中氟喹诺酮耐药性的出现伴随着对β-内酰胺类抗生素的耐药性。
Antimicrob Agents Chemother. 1988 Sep;32(9):1437-8. doi: 10.1128/AAC.32.9.1437.
2
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In vitro and in vivo activity of DL-8280, a new oxazine derivative.新型恶嗪衍生物DL-8280的体外和体内活性
Antimicrob Agents Chemother. 1982 Oct;22(4):548-53. doi: 10.1128/AAC.22.4.548.
2
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid.新型吡啶羧酸AT-2266的体外抗菌特性
Antimicrob Agents Chemother. 1983 May;23(5):641-8. doi: 10.1128/AAC.23.5.641.
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Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria.环丙沙星，一种对需氧菌和厌氧菌均有活性的喹诺酮羧酸化合物。
Antimicrob Agents Chemother. 1984 Mar;25(3):319-26. doi: 10.1128/AAC.25.3.319.
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In vitro activity of ciprofloxacin (Bay o 9867).环丙沙星（拜耳o 9867）的体外活性。
Antimicrob Agents Chemother. 1983 Oct;24(4):568-74. doi: 10.1128/AAC.24.4.568.
5
In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.新型喹啉衍生物Bay 09867与其他抗菌药物的体外活性比较。
Antimicrob Agents Chemother. 1983 Apr;23(4):559-64. doi: 10.1128/AAC.23.4.559.
6
Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes.喹诺酮类、β-内酰胺类和氨基糖苷类药物对多重抗生素耐药性的选择，特别提及不相关药物类别之间的交叉耐药性。
Antimicrob Agents Chemother. 1984 Dec;26(6):797-801. doi: 10.1128/AAC.26.6.797.
7
Comparison of PRAS II, RapID ANA, and API 20A systems for identification of anaerobic bacteria.用于鉴定厌氧菌的PRAS II、RapID ANA和API 20A系统的比较
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Isolation and characterization of norfloxacin-resistant mutants of Escherichia coli K-12.大肠杆菌K-12耐诺氟沙星突变体的分离与鉴定
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9
Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli.大肠杆菌中诺氟沙星耐药性的遗传与生化特征分析
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Ciprofloxacin-resistant Pseudomonas.
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脆弱拟杆菌中氟喹诺酮耐药性的出现伴随着对β-内酰胺类抗生素的耐药性。

Emergence of fluoroquinolone resistance in Bacteroides fragilis accompanied by resistance to beta-lactam antibiotics.

作者信息

Kato N, Miyauchi M, Muto Y, Watanabe K, Ueno K

机构信息

Institute of Anaerobic Bacteriology, Gifu University School of Medicine, Japan.

出版信息

Antimicrob Agents Chemother. 1988 Sep;32(9):1437-8. doi: 10.1128/AAC.32.9.1437.

DOI:10.1128/AAC.32.9.1437
PMID:2848446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC175885/
Abstract

The in vitro susceptibilities of a group of 93 isolates of Bacteroides fragilis collected from 1983 to 1984 to six fluoroquinolones were compared with those of a group of 93 isolates collected from 1986 to 1987. The recently collected strains were less susceptible than the older strains to all of the agents tested. Norfloxacin-resistant (MIC, greater than 100 micrograms/ml) strains were less susceptible to cefoxitin and piperacillin than norfloxacin-susceptible strains.

摘要

将1983年至1984年收集的93株脆弱拟杆菌分离株对6种氟喹诺酮类药物的体外敏感性，与1986年至1987年收集的93株分离株的敏感性进行了比较。最近收集的菌株对所有测试药物的敏感性均低于较老的菌株。耐诺氟沙星（MIC，大于100微克/毫升）的菌株对头孢西丁和哌拉西林的敏感性低于对诺氟沙星敏感的菌株。