脆弱拟杆菌中氟喹诺酮耐药性的出现伴随着对β-内酰胺类抗生素的耐药性。
Emergence of fluoroquinolone resistance in Bacteroides fragilis accompanied by resistance to beta-lactam antibiotics.
作者信息
Kato N, Miyauchi M, Muto Y, Watanabe K, Ueno K
机构信息
Institute of Anaerobic Bacteriology, Gifu University School of Medicine, Japan.
出版信息
Antimicrob Agents Chemother. 1988 Sep;32(9):1437-8. doi: 10.1128/AAC.32.9.1437.
Abstract
The in vitro susceptibilities of a group of 93 isolates of Bacteroides fragilis collected from 1983 to 1984 to six fluoroquinolones were compared with those of a group of 93 isolates collected from 1986 to 1987. The recently collected strains were less susceptible than the older strains to all of the agents tested. Norfloxacin-resistant (MIC, greater than 100 micrograms/ml) strains were less susceptible to cefoxitin and piperacillin than norfloxacin-susceptible strains.
摘要
将1983年至1984年收集的93株脆弱拟杆菌分离株对6种氟喹诺酮类药物的体外敏感性，与1986年至1987年收集的93株分离株的敏感性进行了比较。最近收集的菌株对所有测试药物的敏感性均低于较老的菌株。耐诺氟沙星（MIC，大于100微克/毫升）的菌株对头孢西丁和哌拉西林的敏感性低于对诺氟沙星敏感的菌株。
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